Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniPathway vocabulary mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry P05108 (CP11A_HUMAN), Cholesterol side-chain cleavage enzyme, mitochondrial
Heterozygous mutation in the cholesterol side chain cleavage enzyme (p450scc) gene in a patient with 46,XY sex reversal and adrenal insufficiency.
Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc.
Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.
Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Oxidation of cholesterol to 22beta-hydroxycholesterol
Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol
CYP11A1 cleaves 20a,22b-DHCHOL
Pregnenolone biosynthesis
Defective CYP11A1 does not cleave 20a,22b-DHCHOL