Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry Q88HS1 for Pseudomonas putida KT2440 paaH
-
NCBIfam assigns Q88HS1 to the phenylacetate-pathway PaaH 3-hydroxyacyl-CoA dehydrogenase family.
"NCBIfam; TIGR02279; PaaC-3OHAcCoADH"
-
Q88HS1 matches the 3-hydroxyacyl-CoA dehydrogenase signature.
"PROSITE; PS00067; 3HCDH"
Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
OpenScientist deep-research report for PSEPK paaH
-
The report independently matches Q88HS1 and PP_3282 to an NAD+-dependent 3-hydroxyacyl-CoA dehydrogenase in lower phenylacetate catabolism.
"**PaaH** (gene *paaH*; ordered locus **PP_3282**; UniProt **Q88HS1**) of *Pseudomonas putida* KT2440 is a **soluble, cytoplasmic, NAD⁺-dependent 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)** that acts in the **lower, β-oxidation-like segment of the aerobic phenylacetate (phenylacetyl-CoA) degradation pathway**."
-
Direct target-specific substrate enzymology remains unavailable.
"**No direct enzymology on Q88HS1 itself:** substrate specificity and kinetic parameters are inferred from pathway context and close homologs, not measured for the KT2440 protein."