GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:11563910
Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking.
PMID:14505570
The protein network of HIV budding.
PMID:15024011
Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes.
PMID:16193069
Structural and mechanistic studies of VPS4 proteins.
PMID:16505166
Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.
PMID:16757520
Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4.
PMID:17428789
Phosphatidylethanolamine, a limiting factor of autophagy in yeast strains bearing a defect in the carboxypeptidase Y pathway of vacuolar targeting.
PMID:17928862
ESCRT-III recognition by VPS4 ATPases.
PMID:17940959
Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction.
PMID:18385515
Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly.
PMID:18606141
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.
PMID:18687924
Helical structures of ESCRT-III are disassembled by VPS4.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:19129479
Biochemical analyses of human IST1 and its function in cytokinesis.
PMID:19234443
Membrane scission by the ESCRT-III complex.
PMID:19278657
Three-dimensional structure of AAA ATPase Vps4: advancing structural insights into the mechanisms of endosomal sorting and enveloped virus budding.
PMID:20588296
Membrane budding and scission by the ESCRT machinery: it's all in the neck.
PMID:20616062
Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance.
PMID:22547407
ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting.
PMID:22660413
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
PMID:23105106
Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport.
PMID:23533145
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
PMID:24105262
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles.
PMID:24107264
ESCRT requirements for EIAV budding.
PMID:24482116
ESCRT machinery is required for plasma membrane repair.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:26040712
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
PMID:26040713
ESCRT-III controls nuclear envelope reformation.
PMID:28242692
LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
PMID:9211789
The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment.
Reactome:R-HSA-3159232
Recruitment Of HIV Virion Budding Machinery
Reactome:R-HSA-917693
ESCRT Disassembly
UniProt:O75351
UniProt entry for VPS4B (O75351)
file:human/VPS4B/VPS4B-notes.md
Local curation notes for VPS4B