Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Disruption of an active site hydrogen bond converts human heme oxygenase-1 into a peroxidase.
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia.
Significance of heme oxygenase in prolactin-mediated cell proliferation and angiogenesis in human endothelial cells.
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration.
Involvement of NADPH in the interaction between heme oxygenase-1 and cytochrome P450 reductase.
BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes.
Heme oxygenase-1 modulates the expression of the anti-angiogenic chemokine CXCL-10 in renal tubular epithelial cells.
Expression and characterization of full-length human heme oxygenase-1: the presence of intact membrane-binding region leads to increased binding affinity for NADPH cytochrome P450 reductase.
HO-1 underlies resistance of AML cells to TNF-induced apoptosis.
Differential induction of heme oxygenase-1 against nicotine-induced cytotoxicity via the PI3K, MAPK, and NF-kappa B pathways in immortalized and malignant human oral keratinocytes.
The role of heme oxygenase-1 in T cell-mediated immunity: the all encompassing enzyme.
Decidual expression and maternal serum levels of heme oxygenase 1 are increased in pre-eclampsia.
Oligomerization is crucial for the stability and function of heme oxygenase-1 in the endoplasmic reticulum.
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Transformation of eEF1Bδ into heat-shock response transcription factor by alternative splicing.
MicroRNA-24 regulates vascularity after myocardial infarction.
Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol.
Stanniocalcin 2, forms a complex with heme oxygenase 1, binds hemin and is a heat shock protein.
Haem oxygenase-1 overexpression alters intracellular iron distribution.
Hypoxia-responsive microRNA-101 promotes angiogenesis via heme oxygenase-1/vascular endothelial growth factor axis by targeting cullin 3.
Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells.
APEX Fingerprinting Reveals the Subcellular Localization of Proteins of Interest.
A reference map of the human binary protein interactome.
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Human heme oxygenase cDNA and induction of its mRNA by hemin.
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection.
A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.
Expression and characterization of truncated human heme oxygenase (hHO-1) and a fusion protein of hHO-1 with human cytochrome P450 reductase.
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency.
HMOX1 dimer, HMOX2 cleave heme
SGTA binds Tail-anchored protein
HMOX1 gene produces HMOX1 dimer
HMOX1 translocates from the cytosol to the nucleoplasm
HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane
NFE2L2-dependent HMOX1 gene expression