Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype.
Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.
Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Characterization of the membrane-targeting C1 domain in Pasteurella multocida toxin.
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
The CD46-Jagged1 interaction is critical for human TH1 immunity.
A physical wiring diagram for the human immune system.
Quantitative fragmentomics allow affinity mapping of interactomes.
The human CD46 molecule is a receptor for measles virus (Edmonston strain).
Complement factor I binds to MCP, CR1:C4b, C3b
Factor I inactivates MCP/CR1-bound C4b/C3b
Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins.
Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome.
Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation.
Characterization of human membrane cofactor protein (MCP; CD46) on spermatozoa.
Author Correction: Quantitative fragmentomics allow affinity mapping of interactomes.
UniProt record for human CD46 (P15529)
Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form.
Contribution of the repeating domains of membrane cofactor protein (CD46) of the complement system to ligand binding and cofactor activity.
Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells.