Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic Gene Ontology annotation based on Rhea mapping

Electronic Gene Ontology annotations created by ARBA machine learning models

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

Combined Automated Annotation using Multiple IEA Methods

FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse.

Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction.

Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer.

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.

Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.

Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2.

mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis.

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.

Stress and mTORture signaling.

Steroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epithelia.

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.

Integration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4.

Lkb1 deficiency causes prostate neoplasia in the mouse.

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.

mTORC1 promotes survival through translational control of Mcl-1.

Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.

Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB.

Regulation of myoblast differentiation by the nuclear envelope protein NET39.

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif.

Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.

mTOR signaling in growth control and disease.

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes.

Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.

mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts.

Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis.

Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1.

Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling.

Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.

PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription.

MicroRNA-23a promotes myelination in the central nervous system.

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.

Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.

Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain.

Huntingtin functions as a scaffold for selective macroautophagy.

mLST8 Promotes mTOR-Mediated Tumor Progression.

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy.

miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation.

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

Functional kinomics establishes a critical node of volume-sensitive cation-Cl(-) cotransporter regulation in the mammalian brain.

The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.

mTOR Signaling in Growth, Metabolism, and Disease.

mTORC2 Promotes Tumorigenesis via Lipid Synthesis.

mTOR signaling regulates central and peripheral circadian clock function.

Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes.

Hyperactive Akt-mTOR pathway as a therapeutic target for pain hypersensitivity in Cntnap2-deficient mice.

The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.

The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt.

Picornavirus infection enhances aspartate by the SLC38A8 transporter to promote viral replication.

UniProtKB record for mouse Mtor (Q9JLN9)

Falcon deep research synthesis for mouse Mtor