Gene Ontology annotation through association of InterPro records with GO terms
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Structural insight into how Streptomyces coelicolor maltosyl transferase GlgE binds α-maltose 1-phosphate and forms a maltosyl-enzyme intermediate.
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Biochemical and structural work on Streptomyces GlgE establishes the EC 2.4.99.16 maltose 1-phosphate-dependent maltosyltransferase reaction and double-displacement mechanism conserved by the Pseudomonas ortholog.
"GlgE (EC 2.4.99.16) is an α-maltose 1-phosphate:(1→4)-α-d-glucan 4-α-d-maltosyltransferase of the CAZy glycoside hydrolase 13_3 family."
UniProtKB entry for glgE (Q88FM9)
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UniProt assigns Q88FM9 to PANTHER subfamily PTHR47786:SF2 (GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN).
"PTHR47786:SF2; GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"
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The unreviewed HAMAP record assigns GlgE EC 2.4.99.16/RHEA:42692, identifies alpha-maltose 1-phosphate binding residues, and describes extension of alpha-1,4-glucan in the TreS/Mak/GlgE/GlgB route.
OpenScientist functional-annotation report for glgE
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The report corroborates the maltose-1-phosphate donor, alpha-1,4-glucan acceptor, GH13 transfer mechanism, and TreS-Mak-GlgE-GlgB pathway placement while finding no direct assay of Q88FM9.
PANTHER PTHR47786 family entries
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The experimentally characterized PAINT seed P9WQ17 (Mycobacterium GlgE) is a member of PTHR47786:SF2, the same subfamily that UniProt assigns to Q88FM9.
"PTHR47786:SF2,GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"
PANTHER PAINT annotations for PTHR47786