Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Gene Ontology annotation based on Berkeley BOP standard phylogenetic annotation (IBA)

Gene Ontology annotation based on UniPathway vocabulary mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

GO_REF:0000122

AtSubP analysis

PMID:11532178

Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis.

"the expression of an NCED gene of Arabidopsis, AtNCED3, is induced by drought stress and controls the level of endogenous ABA under drought-stressed conditions."
"antisense suppression and disruption of AtNCED3 gave a drought-sensitive phenotype."

PMID:12834401

Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family.

"A key regulated step in abscisic acid (ABA) biosynthesis in plants is catalyzed by 9-cis epoxycarotenoid dioxygenase (NCED), which cleaves 9-cis xanthophylls to xanthoxin, a precursor of ABA."
"AtNCED2, AtNCED3, and AtNCED6 are found in both stroma and thylakoid membrane-bound compartments."

PMID:15466233

Uncoupling the effects of abscisic acid on plant growth and water relations. Analysis of sto1/nced3, an abscisic acid-deficient but salt stress-tolerant mutant in Arabidopsis.

"Mutant sto1 plants were unable to accumulate ABA following a hyperosmotic stress, although their basal ABA level was only moderately altered."

PMID:16870153

Regulation of ABA level and water-stress tolerance of Arabidopsis by ectopic expression of a peanut 9-cis-epoxycarotenoid dioxygenase gene.

"Ectopic expression of AhNCED1 gene in 129B08/nced3 mutant Arabidopsis (with impaired AtNCED3 gene involved in ABA biosynthesis under water stress) driven by the AtNCED3 promoter restores its ability to accumulate ABA during drought stress, and reverts its hypersensitivity to nonionic osmotic stress and soil drought."

PMID:18854047

Identification, cloning and characterization of sis7 and sis10 sugar-insensitive mutants of Arabidopsis.

"Mutations in the SIS7/NCED3/STO1 gene, which is primarily required for ABA biosynthesis under drought conditions, confer a sugar-insensitive phenotype."

file:ARATH/NCED3/NCED3-uniprot.txt

UniProt entry NCED3_ARATH (Q9LRR7)

"Binds 1 Fe(2+) ion per subunit."

file:ARATH/NCED3/NCED3-deep-research-falcon.md

Falcon (Edison Scientific) deep research report for NCED3

"it catalyzes the xanthoxin-producing cleavage of 9-cis epoxycarotenoids in plastids"
"NCED3 contains conserved iron-chelating histidines"