GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000043
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10791971
Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis.
PMID:11306575
The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component.
PMID:11741979
Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation.
PMID:14500886
Isolation and characterization of human nuclear and cytosolic multisynthetase complexes and the intracellular distribution of p43/EMAPII.
PMID:19131329
Dissection of the structural organization of the aminoacyl-tRNA synthetase complex.
PMID:19289464
Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:22190034
Global landscape of HIV-human protein complexes.
PMID:24312579
Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex.
PMID:24337748
Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:32644155
3-Dimensional architecture of the human multi-tRNA synthetase complex.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Reactome:R-HSA-379861
glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
Reactome:R-HSA-379865
proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
Reactome:R-HSA-379867
aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
Reactome:R-HSA-379893
isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
Reactome:R-HSA-379974
leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
Reactome:R-HSA-379982
glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
Reactome:R-HSA-379993
arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
Reactome:R-HSA-379994
methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
Reactome:R-HSA-380008
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
Reactome:R-HSA-9825759
MAPK-dependent phosphorylation of KARS
file:human/AIMP1/AIMP1-deep-research-falcon.md
Deep research report on AIMP1
PMID:10358004
Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase.
PMID:12237313
Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis.
PMID:17001013
Hormonal activity of AIMP1/p43 for glucose homeostasis.
PMID:17525271
Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases.
PMID:25288775
Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation.
PMID:29379495
AIMp1 Potentiates T(H)1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity.
PMID:39542129
Assembly of the Human Multi-tRNA Synthetase Complex Through Leucine Zipper Motifs.
PMID:10850427
Prostate adenocarcinoma cells release the novel proinflammatory polypeptide EMAP-II in response to stress.
PMID:38975338
The mARS complex: a critical mediator of immune regulation and homeostasis.
PMID:39075051
Structural basis of tRNA recognition by the widespread OB fold.
PMID:39494335
AIMP1-Derived Peptide Secreted from Hair Follicle Stem Cells Promotes Hair Growth by Activating Dermal Papilla Cells.
file:human/AIMP1/AIMP1-notes.md
AIMP1 source-access and curation notes