The research report should be a detailed narrative explaining the function, biological processes, and localization of the gene product. Citations should be given for all claims.
You should prioritize authoritative reviews and primary scientific literature when conducting research. You can supplement
this with annotations you find in gene/protein databases, but these can be outdated or inaccurate.
We are specifically interested in the primary function of the gene - for enzymes, what reaction is catalyzed, and what is the substrate specificity? For transporters, what is the substrate? For structural proteins or adapters, what is the broader structural role? For signaling molecules, what is the role in the pathway.
We are interested in where in or outside the cell the gene product carries out its function.
We are also interested in the signaling or biochemical pathways in which the gene functions. We are less interested in broad pleiotropic effects, except where these elucidate the precise role.
Include evidence where possible. We are interested in both experimental evidence as well as inference from structure, evolution, or bioinformatic analysis. Precise studies should be prioritized over high-throughput, where available.
The literature retrieved and analyzed here consistently refers to Arabidopsis thaliana AUX1 (At2g38120) as an auxin influx carrier (auxin transporter protein 1) in the AUX/LAX family within the AAAP (amino acid/auxin permease) superfamily, matching the UniProt description provided for UniProt Q96247 (auxin transporter protein 1; AUX1/PIR1/WAV5). Evidence includes direct heterologous transport assays, direct auxin binding assays, and AXR4-dependent trafficking studies centered on Arabidopsis AUX1; no conflicting “AUX1” gene from other organisms is used for inference in the claims below. (swarup2012auxlaxfamilyof pages 2-3, yang2006highaffinityauxintransport pages 1-2, carrier2008thebindingof pages 2-4)
Auxin (primarily indole-3-acetic acid, IAA) is a weak acid; at apoplastic pH a fraction of IAA is protonated (IAAH) and can diffuse, but the dominant regulated cellular uptake is via influx carriers such as AUX1/LAX proteins. Reviews emphasize that AUX1/LAX transporters are major auxin influx carriers required to establish auxin gradients that drive development. (swarup2012auxlaxfamilyof pages 2-3, hammes2022auxintransportersabiochemical pages 11-13)
Mechanistic synthesis indicates AUX1 operates as a proton-coupled symporter (H+:IAA−), energized by the plasma-membrane proton motive force. A commonly cited stoichiometry is two protons per IAA− transported, consistent with vesicle/biophysical evidence summarized in a mechanistic review. (singh2018advancesinunderstanding pages 1-3)
Consistent with this model, AUX1-mediated uptake and AUX1–IAA binding show clear pH dependence with optima near mildly acidic pH (approximately the apoplast), supporting physiological relevance at the cell wall interface. (yang2006highaffinityauxintransport pages 1-2, carrier2008thebindingof pages 2-4)
AUX1 is a multi-pass membrane protein; reviews summarize that AUX1 has ~11 transmembrane (TM) segments and belongs to the AAAP superfamily, with topology and evolutionary conservation suggesting an alternating-access transport mechanism typical of proton-driven symporters. (swarup2012auxlaxfamilyof pages 2-3, singh2018advancesinunderstanding pages 6-8)
Direct functional evidence from heterologous expression in Xenopus oocytes demonstrates that AUX1 transports IAA with high affinity and saturable kinetics. (yang2006highaffinityauxintransport pages 1-2)
AUX1-mediated IAA uptake is competitively inhibited by certain auxin analogs/influx inhibitors (e.g., 2,4-D, 1-NOA), but not by some other auxin-related compounds under the conditions tested (e.g., NAA, IBA), supporting selectivity. (yang2006highaffinityauxintransport pages 4-5, yang2006highaffinityauxintransport pages 1-2)
In the Xenopus oocyte system, AUX1 confers >10-fold increased radiolabeled IAA uptake relative to controls and shows Km ≈ 800 nM for IAA uptake. (yang2006highaffinityauxintransport pages 1-2)
A key biochemical advance was the demonstration of direct IAA binding to AUX1 using AUX1 expressed in insect cells and purified membrane fractions. Binding assays yielded a reported Kd ≈ 2.6 µM and Bmax ≈ 11,800 fmol IAA/mg membrane protein, with maximal specific binding around pH 5–6. (carrier2008thebindingof pages 4-5, carrier2008thebindingof pages 2-4, carrier2008thebindingof pages 5-7)
Competition/displacement assays show multiple auxins and inhibitors can displace bound IAA; reported IC50 values include a strong competitor (2-NAA) at approximately 3.6 µM among tested inhibitors/analogs in the study’s table. (carrier2008thebindingof pages 5-7)
A mechanistic review synthesizes independent uptake-permeability estimates (e.g., ~1.4–1.5 µm/s in different experimental contexts), emphasizing that AUX1-mediated influx dominates over passive diffusion at equilibrium in many physiological settings. (singh2018advancesinunderstanding pages 6-8)
AUX1 localizes to the plasma membrane in heterologous expression (EYFP-AUX1 in oocytes), where it mediates pH-dependent, saturable IAA uptake. (yang2006highaffinityauxintransport pages 1-2)
A major recent mechanistic advance (Plant Physiology, Sep 2024) is evidence that AXR4 governs AUX1 trafficking: in axr4 mutants AUX1 is retained/accumulates in the endoplasmic reticulum (ER) rather than reaching the plasma membrane. The 2024 study provides biochemical evidence that AXR4 physically interacts with AUX1 and reduces AUX1 aggregation in a dose-dependent fashion, supporting a model in which AXR4 functions as an ER accessory/chaperone-like factor enabling proper folding/ER exit and plasma-membrane targeting of AUX1. (tidy2024mechanisticinsightinto pages 1-1, tidy2024mechanisticinsightinto pages 5-6)
Notably, the same study extends AXR4 dependence beyond AUX1 to another influx carrier: LAX2 also requires AXR4 for correct localization to the plasma membrane, connecting trafficking regulation to broader auxin transport network behavior. (tidy2024mechanisticinsightinto pages 2-3, tidy2024mechanisticinsightinto pages 1-2)
A recent gravitropism-focused review (Jan 2024) synthesizes that AUX1 is essential for gravitropism and mediates auxin movement from the lateral root cap to the epidermis of the elongation zone, enabling differential growth during bending; the review also highlights that AUX1 function depends on appropriate trafficking/localization and that disruption of AUX1 asymmetry (e.g., via axr4-related mislocalization) weakens gravitropic responses. (tang2024auxinsandenvironmental pages 2-3, tang2024auxinsandenvironmental pages 3-5)
A broader 2024 auxin biology review similarly places AUX1 in gravitropism models and emphasizes coordination with efflux (e.g., PIN2) in environment-sensitive gravitropic responses. (gao2024advancesinplant pages 6-7)
An authoritative AUX/LAX overview reports AUX1 expression in pericycle cells prior to the first periclinal division and notes that aux1 mutants show ~50% reduction in emerged lateral roots, supporting AUX1-mediated auxin uptake as a quantitative determinant of LR development. (swarup2012auxlaxfamilyof pages 5-6)
The AUX/LAX overview reports AUX1 expression in epidermal non-hair cells and links AUX1 to root hair development and planar polarity. Quantitatively, aux1 mutants have shorter root hairs (rescuable by exogenous auxin) and show ~30-fold higher frequency of double-hair formation, indicating disrupted epidermal patterning/polarity. (swarup2012auxlaxfamilyof pages 5-6)
Modeling summarized in the same review suggests AUX1 expression in non-hair cells can drive >10-fold auxin accumulation in those cells relative to adjacent hair cells, and maintain elevated auxin in hair cell files up to ~500 µm from the root apex—an example of how localized influx helps sustain a developmental field. (swarup2012auxlaxfamilyof pages 5-6)
Reviews position AUX1 as contributing to leaf phyllotactic patterning (often with LAX paralogs) and to additional auxin-dependent processes (e.g., apical hook formation, aspects of embryo development), reflecting AUX1’s broader role in shaping local auxin maxima/minima via regulated import. (hammes2022auxintransportersabiochemical pages 11-13, singh2018advancesinunderstanding pages 1-3)
The most direct 2024 advance in the retrieved corpus is the mechanistic dissection of AXR4, proposing and supporting (via interaction and aggregation assays) that AXR4 is not primarily an enzyme modifying AUX1, but rather an ER accessory protein enabling AUX1 (and LAX2) maturation and delivery to the plasma membrane. This provides a clearer molecular explanation for classic auxin-response phenotypes observed in axr4 backgrounds. (tidy2024mechanisticinsightinto pages 1-1, tidy2024mechanisticinsightinto pages 5-6, tidy2024mechanisticinsightinto pages 2-3)
The 2024 gravitropism review highlights AUX1’s role in auxin transfer between tissues and frames AUX1 localization/trafficking as a key layer through which environmental factors can modulate the gravitropic response (e.g., through impacts on transporter localization networks). (tang2024auxinsandenvironmental pages 2-3, tang2024auxinsandenvironmental pages 3-5)
Despite strong kinetic and binding evidence, expert reviews emphasize that the high-resolution structural basis of AUX1 substrate recognition and proton coupling remains a major gap, and topology/alternating-access models remain partly inferential without transporter structures. (singh2018advancesinunderstanding pages 6-8)
AUX1 selectivity and inhibitor sensitivity support practical use of influx inhibitors (e.g., 1-NOA/related compounds) as tools to perturb auxin uptake and dissect developmental programs in vivo, with direct linkage of inhibitor action to root growth outcomes in primary studies. (yang2006highaffinityauxintransport pages 4-5, yang2006highaffinityauxintransport pages 1-2)
The 2024 trafficking study explicitly argues that understanding AXR4-mediated AUX/LAX trafficking could inform strategies to engineer “designer roots” to improve water and nutrient acquisition in crops, i.e., by tuning the abundance/localization of auxin influx carriers at the plasma membrane to reshape root architecture. This is presented as a forward-looking translational implication rather than a completed field deployment. (tidy2024mechanisticinsightinto pages 1-1)
Key quantitative points for functional annotation and modeling include:
The following table compiles the core functional evidence, quantitative parameters, and 2024 regulatory advances with DOI URLs.
| Claim/finding | Evidence type/assay system | Quantitative result(s) | Biological implication | Citation with year + DOI URL |
|---|---|---|---|---|
| AUX1 is a high-affinity auxin influx carrier for IAA | Heterologous expression in Xenopus laevis oocytes; plasma-membrane localization of EYFP-AUX1; radiolabeled ^3H-IAA uptake | AUX1 increased ^3H-IAA uptake by >10-fold vs. water controls; uptake was saturable with Km ~800 nM; aux1-7 and aux1-117 abolished uptake, aux1-102 reduced uptake by ~60% | Establishes AUX1 as a bona fide carrier-mediated IAA importer with physiologically relevant high affinity | Yang et al. 2006, https://doi.org/10.1016/j.cub.2006.04.029 (yang2006highaffinityauxintransport pages 1-2) |
| AUX1 shows selective pharmacology consistent with influx-carrier behavior | Same Xenopus oocyte uptake system plus Arabidopsis root elongation assays | AUX1-mediated uptake inhibited by 2,4-D and 1-NOA; not inhibited by NAA or IBA in the cited assay summary; in roots, 50 nM IAA reduced elongation up to ~80%, while 20 mM 1-NOA produced ~3-fold longer roots than IAA alone | Confirms substrate/inhibitor specificity and links transporter pharmacology to plant growth responses | Yang et al. 2006, https://doi.org/10.1016/j.cub.2006.04.029 (yang2006highaffinityauxintransport pages 4-5, yang2006highaffinityauxintransport pages 1-2) |
| AUX1 directly binds IAA with micromolar affinity | Radioligand binding to HA-AUX1 expressed in Sf9 insect-cell membranes; homologous displacement/saturation analysis | Kd ~2.6 µM; Bmax ~11,800 fmol IAA/mg membrane protein; specific binding in control membranes ~1% of HA-AUX1 membranes | Direct biochemical evidence that AUX1 physically recognizes auxin at affinities comparable to transport measurements | Carrier et al. 2008, https://doi.org/10.1104/pp.108.122044 (carrier2008thebindingof pages 4-5, carrier2008thebindingof pages 1-2, carrier2008thebindingof pages 2-4, carrier2008thebindingof pages 5-7) |
| AUX1–IAA interaction is pH dependent and consistent with transport of anionic auxin near apoplastic pH | Sf9 membrane binding assays across buffered pH range | Binding optimum between pH 5.0 and 6.0; rapid association reported, with binding half-life on the order of seconds in assay summaries; >90% specific binding retained after 60 min in dissociation conditions | Supports the proton-coupled import model and physiological relevance at the acidic cell wall/apoplastic interface | Carrier et al. 2008, https://doi.org/10.1104/pp.108.122044 (carrier2008thebindingof pages 4-5, carrier2008thebindingof pages 2-4, carrier2008thebindingof pages 5-7) |
| Auxin analogs and influx inhibitors displace IAA from AUX1 | Competitive displacement of ^3H-IAA from AUX1-containing membranes | All tested auxins/inhibitors displaced >95% of bound IAA; reported IC50 values included approximately 39.7 µM, 53.6 µM, 70.8 µM, 3.6 µM, 32.4 µM, with 2-NAA ~3.6 µM among the strongest competitors in the reported table | Refines substrate-recognition and inhibitor-binding landscape of AUX1 | Carrier et al. 2008, https://doi.org/10.1104/pp.108.122044 (carrier2008thebindingof pages 4-5, carrier2008thebindingof pages 5-7, carrier2008thebindingof pages 7-7) |
| AUX1 contributes quantitatively to lateral root development | Review synthesis of genetic and developmental studies in Arabidopsis | aux1 mutants show ~50% reduction in emerged lateral roots | Indicates AUX1-mediated auxin uptake is required for normal lateral root emergence/development | Swarup & Péret 2012, https://doi.org/10.3389/fpls.2012.00225 (swarup2012auxlaxfamilyof pages 5-6) |
| AUX1 in non-hair/epidermal cells sustains root-hair patterning and polarity | Review synthesis of expression, mutant, rescue, and modeling studies | aux1 mutants show ~30-fold higher frequency of double-hair formation; exogenous auxin rescues shorter root hairs | Shows AUX1 helps establish auxin distribution needed for correct root-hair elongation and planar polarity | Swarup & Péret 2012, https://doi.org/10.3389/fpls.2012.00225 (swarup2012auxlaxfamilyof pages 5-6) |
| Modeling and tissue-expression data support AUX1-mediated auxin focusing in epidermal patterning | Review synthesis of computational and experimental studies | AUX1 expression in non-hair cells can drive >10-fold auxin accumulation relative to adjacent hair cells; elevated auxin in hair-cell files can be maintained up to ~500 µm from the root apex | Explains how localized influx can shape spatial auxin gradients over multicellular distances | Swarup & Péret 2012, https://doi.org/10.3389/fpls.2012.00225 (swarup2012auxlaxfamilyof pages 5-6) |
| AUX1/LAX transport is proton-coupled and likely stoichiometric with two protons per IAA− | Mechanistic review integrating vesicle transport, topology, and biophysical work | Reported stoichiometry: 2 H+ per IAA−; summarized AUX1 affinity for IAA ~0.5 µM and influx permeability ~1.4 µm/s; related measurements include 1.5 µm/s IAA uptake permeability in Arabidopsis protoplasts | Supports the current model of AUX1 as an energized H+:IAA− symporter that dominates cellular auxin influx | Singh et al. 2018, https://doi.org/10.3390/ijms19113391 (singh2018advancesinunderstanding pages 1-3, singh2018advancesinunderstanding pages 6-8, singh2018advancesinunderstanding pages 8-10) |
| AXR4 is required for correct AUX1 plasma-membrane targeting | 2024 mechanistic study using Arabidopsis mutants, immunolocalization, heterologous expression, and biochemical interaction assays | In axr4, AUX1 accumulates in the ER rather than the plasma membrane; AXR4–AUX1 interaction detected biochemically; AXR4 reduced AUX1 aggregation in a dose-dependent manner | Identifies AXR4 as an ER accessory/chaperone-like factor that enables functional AUX1 deployment to the plasma membrane | Tidy et al. 2024, https://doi.org/10.1093/plphys/kiad506 (tidy2024mechanisticinsightinto pages 1-1, tidy2024mechanisticinsightinto pages 5-6, tidy2024mechanisticinsightinto pages 1-2) |
| AXR4 trafficking control extends beyond AUX1 and has applied significance | Same 2024 Plant Physiology study; localization and phenotype analyses | LAX2 also shows ER retention/mislocalization in axr4; mutated AXR4 transgenes largely restored AUX1 PM localization, with one allele showing partial rescue | Suggests that manipulating AXR4-dependent AUX/LAX trafficking could be used to engineer root system traits (“designer roots”) for nutrient/water acquisition | Tidy et al. 2024, https://doi.org/10.1093/plphys/kiad506 (tidy2024mechanisticinsightinto pages 5-6, tidy2024mechanisticinsightinto pages 2-3, tidy2024mechanisticinsightinto pages 3-4, tidy2024mechanisticinsightinto pages 4-5) |
Table: This table compiles core experimental and review-supported evidence for Arabidopsis AUX1 function, kinetics, localization, and developmental roles. It highlights the most cited quantitative findings and the key 2024 mechanistic advance on AXR4-dependent trafficking.
While the evidence base here is strong for kinetics/binding, trafficking regulation, and core developmental roles, several finer-grained statements commonly associated with AUX1 (e.g., specific polarity patterns in protophloem, detailed cell-by-cell localization maps, or comprehensive post-translational modification control) are only partially supported in the retrieved excerpts and would require additional targeted retrieval of the original localization papers. (lankova2011molecularmechanismof pages 25-29, singh2018advancesinunderstanding pages 6-8)
References
(swarup2012auxlaxfamilyof pages 2-3): Ranjan Swarup and Benjamin Péret. Aux/lax family of auxin influx carriers—an overview. Frontiers in Plant Science, Oct 2012. URL: https://doi.org/10.3389/fpls.2012.00225, doi:10.3389/fpls.2012.00225. This article has 395 citations.
(yang2006highaffinityauxintransport pages 1-2): Yaodong Yang, Ulrich Z. Hammes, Christopher G. Taylor, Daniel P. Schachtman, and Erik Nielsen. High-affinity auxin transport by the aux1 influx carrier protein. Current Biology, 16:1123-1127, Jun 2006. URL: https://doi.org/10.1016/j.cub.2006.04.029, doi:10.1016/j.cub.2006.04.029. This article has 539 citations and is from a highest quality peer-reviewed journal.
(carrier2008thebindingof pages 2-4): David J. Carrier, Norliza Tendot Abu Bakar, Ranjan Swarup, Richard Callaghan, Richard M. Napier, Malcolm J. Bennett, and Ian D. Kerr. The binding of auxin to the arabidopsis auxin influx transporter aux11[oa]. Plant Physiology, 148:529-535, Jul 2008. URL: https://doi.org/10.1104/pp.108.122044, doi:10.1104/pp.108.122044. This article has 89 citations and is from a highest quality peer-reviewed journal.
(hammes2022auxintransportersabiochemical pages 11-13): Ulrich Z. Hammes, Angus S. Murphy, and Claus Schwechheimer. Auxin transporters-a biochemical view. Cold Spring Harbor perspectives in biology, 14:a039875, Jun 2022. URL: https://doi.org/10.1101/cshperspect.a039875, doi:10.1101/cshperspect.a039875. This article has 93 citations and is from a peer-reviewed journal.
(singh2018advancesinunderstanding pages 1-3): Gaurav Singh, Katarzyna Retzer, Stanislav Vosolsobě, and Richard Napier. Advances in understanding the mechanism of action of the auxin permease aux1. International Journal of Molecular Sciences, 19:3391, Oct 2018. URL: https://doi.org/10.3390/ijms19113391, doi:10.3390/ijms19113391. This article has 37 citations.
(singh2018advancesinunderstanding pages 6-8): Gaurav Singh, Katarzyna Retzer, Stanislav Vosolsobě, and Richard Napier. Advances in understanding the mechanism of action of the auxin permease aux1. International Journal of Molecular Sciences, 19:3391, Oct 2018. URL: https://doi.org/10.3390/ijms19113391, doi:10.3390/ijms19113391. This article has 37 citations.
(yang2006highaffinityauxintransport pages 4-5): Yaodong Yang, Ulrich Z. Hammes, Christopher G. Taylor, Daniel P. Schachtman, and Erik Nielsen. High-affinity auxin transport by the aux1 influx carrier protein. Current Biology, 16:1123-1127, Jun 2006. URL: https://doi.org/10.1016/j.cub.2006.04.029, doi:10.1016/j.cub.2006.04.029. This article has 539 citations and is from a highest quality peer-reviewed journal.
(carrier2008thebindingof pages 4-5): David J. Carrier, Norliza Tendot Abu Bakar, Ranjan Swarup, Richard Callaghan, Richard M. Napier, Malcolm J. Bennett, and Ian D. Kerr. The binding of auxin to the arabidopsis auxin influx transporter aux11[oa]. Plant Physiology, 148:529-535, Jul 2008. URL: https://doi.org/10.1104/pp.108.122044, doi:10.1104/pp.108.122044. This article has 89 citations and is from a highest quality peer-reviewed journal.
(carrier2008thebindingof pages 5-7): David J. Carrier, Norliza Tendot Abu Bakar, Ranjan Swarup, Richard Callaghan, Richard M. Napier, Malcolm J. Bennett, and Ian D. Kerr. The binding of auxin to the arabidopsis auxin influx transporter aux11[oa]. Plant Physiology, 148:529-535, Jul 2008. URL: https://doi.org/10.1104/pp.108.122044, doi:10.1104/pp.108.122044. This article has 89 citations and is from a highest quality peer-reviewed journal.
(tidy2024mechanisticinsightinto pages 1-1): Alison Tidy, Norliza Abu Bakar, David Carrier, Ian D Kerr, Charlie Hodgman, Malcolm J Bennett, and Ranjan Swarup. Mechanistic insight into the role of auxin resistance4 in trafficking of auxin1 and like aux1-2. Plant Physiology, 194:422-433, Sep 2024. URL: https://doi.org/10.1093/plphys/kiad506, doi:10.1093/plphys/kiad506. This article has 6 citations and is from a highest quality peer-reviewed journal.
(tidy2024mechanisticinsightinto pages 5-6): Alison Tidy, Norliza Abu Bakar, David Carrier, Ian D Kerr, Charlie Hodgman, Malcolm J Bennett, and Ranjan Swarup. Mechanistic insight into the role of auxin resistance4 in trafficking of auxin1 and like aux1-2. Plant Physiology, 194:422-433, Sep 2024. URL: https://doi.org/10.1093/plphys/kiad506, doi:10.1093/plphys/kiad506. This article has 6 citations and is from a highest quality peer-reviewed journal.
(tidy2024mechanisticinsightinto pages 2-3): Alison Tidy, Norliza Abu Bakar, David Carrier, Ian D Kerr, Charlie Hodgman, Malcolm J Bennett, and Ranjan Swarup. Mechanistic insight into the role of auxin resistance4 in trafficking of auxin1 and like aux1-2. Plant Physiology, 194:422-433, Sep 2024. URL: https://doi.org/10.1093/plphys/kiad506, doi:10.1093/plphys/kiad506. This article has 6 citations and is from a highest quality peer-reviewed journal.
(tidy2024mechanisticinsightinto pages 1-2): Alison Tidy, Norliza Abu Bakar, David Carrier, Ian D Kerr, Charlie Hodgman, Malcolm J Bennett, and Ranjan Swarup. Mechanistic insight into the role of auxin resistance4 in trafficking of auxin1 and like aux1-2. Plant Physiology, 194:422-433, Sep 2024. URL: https://doi.org/10.1093/plphys/kiad506, doi:10.1093/plphys/kiad506. This article has 6 citations and is from a highest quality peer-reviewed journal.
(tang2024auxinsandenvironmental pages 2-3): Z. TANG, Y. ZHANG, Y. MA, D. ZHAO, J. DONG, and H. ZHANG. Auxins and environmental factors regulate root gravitropism. Biologia plantarum, 68:12-21, Jan 2024. URL: https://doi.org/10.32615/bp.2023.016, doi:10.32615/bp.2023.016. This article has 4 citations and is from a peer-reviewed journal.
(tang2024auxinsandenvironmental pages 3-5): Z. TANG, Y. ZHANG, Y. MA, D. ZHAO, J. DONG, and H. ZHANG. Auxins and environmental factors regulate root gravitropism. Biologia plantarum, 68:12-21, Jan 2024. URL: https://doi.org/10.32615/bp.2023.016, doi:10.32615/bp.2023.016. This article has 4 citations and is from a peer-reviewed journal.
(gao2024advancesinplant pages 6-7): Jianshuang Gao, Shunyao Zhuang, and Weiwei Zhang. Advances in plant auxin biology: synthesis, metabolism, signaling, interaction with other hormones, and roles under abiotic stress. Plants, 13:2523, Sep 2024. URL: https://doi.org/10.3390/plants13172523, doi:10.3390/plants13172523. This article has 72 citations.
(swarup2012auxlaxfamilyof pages 5-6): Ranjan Swarup and Benjamin Péret. Aux/lax family of auxin influx carriers—an overview. Frontiers in Plant Science, Oct 2012. URL: https://doi.org/10.3389/fpls.2012.00225, doi:10.3389/fpls.2012.00225. This article has 395 citations.
(carrier2008thebindingof pages 1-2): David J. Carrier, Norliza Tendot Abu Bakar, Ranjan Swarup, Richard Callaghan, Richard M. Napier, Malcolm J. Bennett, and Ian D. Kerr. The binding of auxin to the arabidopsis auxin influx transporter aux11[oa]. Plant Physiology, 148:529-535, Jul 2008. URL: https://doi.org/10.1104/pp.108.122044, doi:10.1104/pp.108.122044. This article has 89 citations and is from a highest quality peer-reviewed journal.
(carrier2008thebindingof pages 7-7): David J. Carrier, Norliza Tendot Abu Bakar, Ranjan Swarup, Richard Callaghan, Richard M. Napier, Malcolm J. Bennett, and Ian D. Kerr. The binding of auxin to the arabidopsis auxin influx transporter aux11[oa]. Plant Physiology, 148:529-535, Jul 2008. URL: https://doi.org/10.1104/pp.108.122044, doi:10.1104/pp.108.122044. This article has 89 citations and is from a highest quality peer-reviewed journal.
(singh2018advancesinunderstanding pages 8-10): Gaurav Singh, Katarzyna Retzer, Stanislav Vosolsobě, and Richard Napier. Advances in understanding the mechanism of action of the auxin permease aux1. International Journal of Molecular Sciences, 19:3391, Oct 2018. URL: https://doi.org/10.3390/ijms19113391, doi:10.3390/ijms19113391. This article has 37 citations.
(tidy2024mechanisticinsightinto pages 3-4): Alison Tidy, Norliza Abu Bakar, David Carrier, Ian D Kerr, Charlie Hodgman, Malcolm J Bennett, and Ranjan Swarup. Mechanistic insight into the role of auxin resistance4 in trafficking of auxin1 and like aux1-2. Plant Physiology, 194:422-433, Sep 2024. URL: https://doi.org/10.1093/plphys/kiad506, doi:10.1093/plphys/kiad506. This article has 6 citations and is from a highest quality peer-reviewed journal.
(tidy2024mechanisticinsightinto pages 4-5): Alison Tidy, Norliza Abu Bakar, David Carrier, Ian D Kerr, Charlie Hodgman, Malcolm J Bennett, and Ranjan Swarup. Mechanistic insight into the role of auxin resistance4 in trafficking of auxin1 and like aux1-2. Plant Physiology, 194:422-433, Sep 2024. URL: https://doi.org/10.1093/plphys/kiad506, doi:10.1093/plphys/kiad506. This article has 6 citations and is from a highest quality peer-reviewed journal.
(lankova2011molecularmechanismof pages 25-29): M Laňková. Molecular mechanism of transport of plant hormone auxin into cells. Unknown journal, 2011.