Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Combined Automated Annotation using Multiple IEA Methods

Alternative splicing of GAD67 results in the synthesis of a third form of glutamic-acid decarboxylase in human islets and other non-neural tissues.

Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.

Towards a proteome-scale map of the human protein-protein interaction network.

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

Next-generation sequencing to generate interactome datasets.

A proteome-scale map of the human interactome network.

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

A reference map of the human binary protein interactome.

Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures.

PXLP-K405-GAD1 decarboxylates L-Glu to form GABA

Synthesis of GABA by GAD2

Release of GABA at the synapse

GABA loaded synaptic vesicle Docking and Priming

UniProt entry Q99259 (DCE1_HUMAN), Glutamate decarboxylase 1