Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Combined Automated Annotation using Multiple IEA Methods
DNA-binding specificities of human transcription factors.
A reference map of the human binary protein interactome.
ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation.
Phosphorylated ERF translocates to the cytosol
Mapk1 (Erk2) phosphorylates ERF
ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression.
Transcriptional repressor erf determines extraembryonic ectoderm differentiation.
Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis.