ILV6 notes (YCL009C, P25605)

• Regulatory (small) subunit of mitochondrial AHAS [UniProt:P25605].
• Stimulates Ilv2 and confers valine inhibition [PMID:10213630 "Reconstitution studies showed that the ilv6 protein stimulates the catalytic activity of the ilv2 protein by up to 7-fold"; "confers upon it sensitivity to inhibition by valine"].
• Mitochondrial with transit peptide removal PMID:10213630
• Deletion abolishes valine feedback inhibition PMID:8972574
• Fungal-specific insert forms MgATP site PMID:16390333
• Mitochondrial nucleoid association from an mtDNA-associated protein screen PMID:15692048 (kept as non-core).

Curation observations

• Core MF: GO:1990610 acetolactate synthase regulator activity; contributes_to GO:0003984.
• SSA2 protein-binding rows (HTP) removed as uninformative.
• GO:0030234 enzyme regulator activity kept non-core (parent of GO:1990610).