GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/gcvH2/gcvH2-uniprot.txt

UniProtKB entry for gcvH2 (Q88CI8)

The reviewed HAMAP-backed record identifies a covalently lipoylated GcvH carrier that transfers the methylamine intermediate from P to T protein.

file:PSEPK/gcvH2/gcvH2-goa.tsv

QuickGO GOA annotations for gcvH2

file:interpro/panther/PTHR11715/PTHR11715-metadata.yaml

PANTHER glycine cleavage H-protein family metadata

PMID:27303730

GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1.

The P. aeruginosa gcvH2-gcvP2-glyA2-sdaA-gcvT2 genes form a glycine-responsive operon.

"these five genes are transcribed together as a single operon"

PMID:23457254

Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.

Inactivation of PA2449/GcsR disrupted glycine assimilation and altered expression of the GCS gene set in P. aeruginosa.

"The inactivation of the PA2449 gene was found to influence the transcription of a core set of genes encoding a glycine cleavage system, serine hydroxymethyltransferase, and serine dehydratase."

file:projects/P_PUTIDA/deep-research/PSEPK__glycine_cleavage_system__ppu00260-deep-research-openscientist.md

OpenScientist PSEPK glycine cleavage system synthesis

file:modules/glycine_cleavage_system.yaml

Glycine cleavage system module