Deep research: just deep-research-falcon worm gcy-8 --fallback perplexity-lite failed
(falcon killed at the 600 s timeout; perplexity provider not available in this environment).
No deep-research file was created. Review based on cached publications in publications/,
the UniProt record, and GOA.
Annotation actions: {'MARK_AS_OVER_ANNOTATED': 1, 'ACCEPT': 20, 'REMOVE': 1, 'KEEP_AS_NON_CORE': 10}
Key evidence:
- AFD-specific GCY-8/18/23 subfamily, sensory-ending localization PMID:16415369
- Direct cyclase activity and Cl- inhibition PMID:27062922
- GCY-8 alone needed for execution of isothermal tracking and AFD responses to oscillating temperature PMID:21315599
- Microvilli shape control via cGMP/WSP-1 PMID:27062922
- Protein kinase activity (IEA) REMOVED: kinase-homology domain predicted catalytically inactive (UniProt).
- Peptide receptor activity IBA marked over-annotated (no peptide ligand; only known ECD regulator is inhibitory Cl-).