Gene Ontology annotation through association of InterPro records with GO terms
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Systematic identification of conserved bacterial c-di-AMP receptor proteins.
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KtrA is the potassium transporter-gating component and a direct c-di-AMP receptor.
"Using an
affinity pull-down assay we identified the potassium transporter-gating
component KtrA as a c-di-AMP receptor protein"
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The RCK_C domain contains the c-di-AMP binding site.
"We defined the c-di-AMP binding activity within KtrA to the RCK_C
(regulator of conductance of K(+)) domain."
The Ktr potassium transport system in Staphylococcus aureus and its role in cell physiology, antimicrobial resistance and pathogenesis.
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USA300 LAC has one KtrA regulator acting with the KtrB and KtrD conducting channels.
"one regulatory protein and two ion-conducting channels required for K+-limited growth of S. aureus in alkaline conditions."