Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Combined Automated Annotation using Multiple IEA Methods
The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A.
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation.
Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2.
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK.
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
ATF5 increases cisplatin-induced apoptosis through up-regulation of cyclin D3 transcription in HeLa cells.
Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization.
ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation.
Regulation of TIP60 by ATF2 modulates ATM activation.
IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription.
cJun modulates Ggamma-globin gene expression via an upstream cAMP response element.
Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays.
JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter.
A comprehensive resource of interacting protein regions for refining human transcription factor networks.
An atlas of combinatorial transcriptional regulation in mouse and man.
In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo.
Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells.
Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.
PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.
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PKC-epsilon directs ATF2 nuclear localization. Under genotoxic stress, ATF2 exports to mitochondrial outer membrane where it perturbs HK1-VDAC1 complex, promotes apoptosis. Dual oncogenic (nuclear) and tumor suppressor (mitochondrial) functions.
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.
MicroRNA-204 is required for differentiation of human-derived cardiomyocyte progenitor cells.
Networks of bZIP protein-protein interactions diversified over a billion years of evolution.
Inducible interleukin 32 (IL-32) exerts extensive antiviral function via selective stimulation of interferon λ1 (IFN-λ1).
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.
A proteome-scale map of the human interactome network.
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Combinatorial bZIP dimers display complex DNA-binding specificity landscapes.
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Architecture of the human interactome defines protein communities and disease networks.
MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1.
CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas.
Characterization of functional domains of an embryonic stem cell coactivator UTF1 which are conserved and essential for potentiation of ATF-2 activity.
Phosphorylated MAPKs phosphorylate ATF-2
Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.
ATF2 acetylates histone H2B, H4
TP53 and AP-1 bind the MSH2 promoter
p-T69,T71-ATF2 binds PTEN gene promoter
Binding of AP1 transcriptional activator complexes to CCND1 promoter
ATF4 and phospho-ATF2 bind the DDIT3 promoter