Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

UniProtKB Q00266 (METK1_HUMAN) S-adenosylmethionine synthase isoform type-1

Methionine adenosyltransferase I/III deficiency: novel mutations and clinical variations.

Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.

Structure and function study of the complex that synthesizes S-adenosylmethionine.

A proteome-scale map of the human interactome network.

Architecture of the human interactome defines protein communities and disease networks.

A reference map of the human binary protein interactome.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism.

Multimodal cell maps as a foundation for structural and functional genomics.

MAT1A multimers transfer Ado from ATP to L-Met

SeMet is converted to AdoSeMet by MAT

Defective MAT1A does not transfer Ado from ATP to L-Met