Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA).
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The PctA ligand binding region binds 17 L-amino acids.
"We show that the recombinant ligand binding regions (LBRs) of PctA, PctB and PctC bind 17, 5 and 2 l-amino acids respectively."
Genetic identification of chemotactic transducers for amino acids in Pseudomonas aeruginosa.
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Cloned pctA restores chemotaxis to 18 L-amino acids in a strain lacking the pct region.
"The pctA gene restored the ability of strain PCT2 to respond to 18 L-amino acids, suggesting that PctA plays a major role in detecting L-amino acids in P. aeruginosa."
Identification of chemosensory proteins for trichloroethylene in Pseudomonas aeruginosa.
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PctA contributes to repellent responses to chloroform and methylthiocyanate.
"This result demonstrates that PctA, PctB and PctC are also involved in repellent responses to chloroform and methylthiocyanate."