Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells.
Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.
A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation.
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.
Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Membrane scission by the ESCRT-III complex.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Membrane budding and scission by the ESCRT machinery: it's all in the neck.
Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance.
Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15.
Toward an understanding of the protein interaction network of the human liver.
Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
ESCRT machinery is required for plasma membrane repair.
Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
A proteome-scale map of the human interactome network.
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
ESCRT-III controls nuclear envelope reformation.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.
Architecture of the human interactome defines protein communities and disease networks.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission.
Recruitment Of HIV Virion Budding Machinery
UniProtKB entry for human CHMP5
N(ε)-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function.
Local curation notes for CHMP5
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Local synthesis identifies CHMP5-LIP5/VTA1-VPS4 regulation of ESCRT-III recycling plus MVB sorting as core, with viral, nuclear-envelope, cytokinesis, repair, NOD2, and infection/autophagy contexts treated as secondary or over-annotated where appropriate.