Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Combined Automated Annotation using Multiple IEA Methods
Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism.
-
Purified P. aeruginosa LolA accepts lipoproteins released by LolCDE, and LolB then inserts them into the outer membrane.
"When incubated in the presence of ATP and a LolA homologue, the reconstituted LolCDE homologue released lipoproteins, leading to the formation of a LolA-lipoprotein complex."
In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa.
-
lolA is essential in P. aeruginosa; LolA depletion increases SDS sensitivity and partly reduces virulence.
"In the whole, this experiment demonstrates that LptH and, to a lesser extent, LolA are the only proteins here investigated with a relevant role in cell envelope stability."
UniProt entry Q9I0M4 (LOLA_PSEAE)