UniProtKB entry for PP_2634
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UniProt carries the generic submitted name "Cellulose synthase" for PP_2634, but its InterPro/Pfam/NCBIfam cross-references identify a BcsQ/YhjQ-family P-loop NTPase.
"DR InterPro; IPR017746; Cellulose_synthase_operon_BcsQ."
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PP_2634 has P-loop NTPase-family signatures and no BcsA-like GT2 cellulose synthase catalytic annotation.
"DR InterPro; IPR027417; P-loop_NTPase."
QuickGO GOA annotations for PP_2634
BcsQ is an essential component of the Escherichia coli cellulose biosynthesis apparatus that localizes at the bacterial cell pole.
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The primary BcsQ paper shows that yhjQ/BcsQ is essential for cellulose biosynthesis and polar localization in the enterobacterial reference system.
"we show that yhjQ, but not yhjR, is essential for cellulose biosynthesis; it has therefore been renamed bcsQ"
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The same paper identifies BcsQ as a MinD homolog with polar localization.
"we demonstrate that BcsQ, a MinD homologue, displays a polar localization"
Architecture and regulation of an enterobacterial cellulose secretion system.
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Cryo-EM work supports BcsQ as part of the assembled Bcs macrocomplex and its ATP-dependent regulation.
"assembled Bcs macrocomplex"
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The abstract reports ATP-dependent regulation of the cellulose secretion system.
"unexpected subunit stoichiometry, multisite c-di-GMP recognition, and ATP-dependent regulation"
Structural basis for synthase activation and cellulose modification in the E. coli Type II Bcs secretion system.
Transcriptional organization, regulation and functional analysis of flhF and fleN in Pseudomonas putida.
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P. putida-specific work shows c-di-GMP/FleQ/FleN regulation of the bcs promoter, placing PP_2634's operon in the biofilm regulatory program.
"PbcsD was negatively regulated by FleQ and FleN, and repression was antagonized by c-di-GMP"
Cell-cell and cell-surface interactions mediated by cellulose and a novel exopolysaccharide contribute to Pseudomonas putida biofilm formation and fitness under water-limiting conditions.
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P. putida-specific physiology supports the bcs system's contribution to rhizosphere colonization and water-stress response.
"formation and stability, although it does contribute to rhizosphere colonization"
OpenScientist gene research for PP_2634
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OpenScientist identifies PP_2634/Q88JL5 as BcsQ, a MinD/ParA-family P-loop ATPase accessory factor, and flags the "Cellulose synthase" submitted name as a mis-annotation.
"PP_2634 is **BcsQ**, an accessory **MinD/ParA-family P-loop ATPase**"