MDH1 notes (P17505, YKL085W)

• Mitochondrial TCA-cycle MDH PMID:3312168
• Null phenotype PMID:3312168
• Biochemistry of interface mutants PMID:1898005
• In vivo interaction with Cit1p PMID:10777592
• Matrix location [UniProt:P17505]; mitochondrial supercomplex PMID:11502169
• mRNA binding via RIP-Chip PMID:21124907

Decisions

• Cytosol RCA from superpathway PWY3O-94 -> REMOVE. Cytoplasm IBA/ARBA -> over-annotated (uninformative). Protein binding (Ssa2, HTP) -> REMOVE.
• Module note: YeastCyc puts MDH1 into "gluconeogenesis I"; MDH1 is the TCA-cycle isozyme; the gluconeogenic cytosolic step is MDH2.