velB (Aspergillus nidulans) — curation notes

UniProt C8VTS4 (VELB_EMENI). Velvet-family regulator; hub of two complexes.
Member of the conidiation_regulatory_cascade module (velvet maturation tier).

• VelB-VeA-LaeA (dark) velvet complex promotes sexual development + secondary
  metabolism; VosA-VelB controls spore maturation/trehalose. PMID:18556559.
• NF-kB-like DNA-binding regulator PMID:24391470; positively regulates sexual
  sporulation and ST biosynthesis, negatively regulates conidiation.
• GO:0045461 (sterigmatocystin biosynthetic process) marked over-annotation (VelB
  is a regulator; use GO:0010914). Trehalose/light roles kept non-core.
• Core MF GO:0003700 proposed (not yet in GOA).

2026-10-01 re-review (GOA refresh)

• No new or vanished GOA rows.
• Protein binding IPI (PMID:24391470) changed KEEP_AS_NON_CORE -> MODIFY to GO:0046982 protein
  heterodimerization activity: the paper solves the VosA-VelB velvet-domain heterodimer structure.
• Core MF changed from GO:0003700 (asserted directly) to molecular_function GO:0046982 plus
  contributes_to GO:0003700: in EMSA "VelB alone at least does not bind the brlA promoter"
  PMID:24391470, whereas the VosA-VelB heterodimer does. Description adjusted accordingly.
• Added supporting text to the nucleus/cytoplasm IDA rows from PMID:21152013.