Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Combined Automated Annotation using Multiple IEA Methods

RGD ISO annotations to rat from other mammalian species

Differential cellular expression of isoforms of inositol 1,4,5-triphosphate receptors in neurons and glia in brain.

Single-channel properties in endoplasmic reticulum membrane of recombinant type 3 inositol trisphosphate receptor.

Intracellular signal transduction during gastrin-induced histamine secretion in rat gastric ECL cells.

Functional characterization of mammalian inositol 1,4,5-trisphosphate receptor isoforms.

Translational mobility of the type 3 inositol 1,4,5-trisphosphate receptor Ca2+ release channel in endoplasmic reticulum membrane.

Signaling proteins in the axoglial apparatus of sciatic nerve nodes of Ranvier.

Protein kinase C decreases the apparent affinity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells.

Protein kinase A increases the binding affinity and the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells.

Inositol 1,4,5 trisphosphate receptor and chromogranin B are concentrated in different regions of the hippocampus.

Characterization of ryanodine receptors in rat colonic epithelium.

Functional ryanodine receptors in the plasma membrane of RINm5F pancreatic beta-cells.

Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinase.

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

Differential distribution, clustering, and lateral diffusion of subtypes of the inositol 1,4,5-trisphosphate receptor.

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium.

Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues.

IP3 binds to the IP3 receptor, opening the Ca2+ channel

Calcium release from intracellular stores by IP3 receptor activation

UniProtKB Q63269 (ITPR3_RAT) flat file

Itpr3 manual literature synthesis