Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.
Acetylation-dependent signal transduction for type I interferon receptor.
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage.
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Architecture of the human interactome defines protein communities and disease networks.
Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency.
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Loss-of-function IRF9 abolishes ISGF3 formation, ISRE binding and ISRE-driven transcription in human cells; rescued by wild-type IRF9.
"Her cells activate gamma-activated factor (GAF) STAT1 homodimers but not IFN-stimulated gene factor 3 (ISGF3) trimers (STAT1/STAT2/IRF9) in response to IFN-α2b"
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
ISGF3 binds the ISRE promoter elements in IFN-stimulated genes
Expression of IFN-induced genes
Expression of IFNG-stimulated genes
Translocation of ISGF3 complex to nucleus
Interaction of IRF9 with p-STAT2:p-STAT1
p-STAT1 dimer binds KPNA1
p-STAT1dimer:KPNA1 binds KPNB1
Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.
Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies.
Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation.
Impaired control of multiple viral infections in a family with complete IRF9 deficiency.
The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9.
UniProt record for IRF9 (Q00978)