PEA15: human–horse sequence comparison

Global alignment of cached UniProt sequences gives 130/130 identical paired residues (100.0%). Paired coverage is 100.0% of human Q15121 (130 aa) and 73.9% of horse A0A9L0RWM8 (176 aa).

Reproduce from the repository root with uv run python genes/HORSE/PEA15/PEA15-bioinformatics/align.py (Biopython). The full alignment is in alignment.txt; sequence hashes and scoring parameters are in results.json.

This measures conservation between the identified records. It is not a reciprocal orthology analysis and does not itself validate a functional annotation. Interpret it alongside locus identifiers, domain architecture and primary literature. The sequences are current cached UniProt records, not independently recovered prediction-time inputs.

Human feature correspondence

These mappings report sequence conservation only; they do not validate targeting, activity or annotation transfer.

Human feature Human positions Paired horse positions Identical / paired