Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Disruption of SMIM1 causes the Vel- blood type.

Homozygosity for a null allele of SMIM1 defines the Vel-negative blood group phenotype.

SMIM1 is a type II transmembrane phosphoprotein and displays the Vel blood group antigen at its carboxyl-terminus.

A reference map of the human binary protein interactome.

SMIM1 underlies the Vel blood group and influences red blood cell traits.

SMIM1 absence is associated with reduced energy expenditure and excess weight.

SMIM1, carrier of the Vel blood group, is a tail-anchored transmembrane protein and readily forms homodimers in a cell-free system.

Dimerization of small integral membrane protein 1 promotes cell surface presentation of the Vel blood group epitope.

SMIM1 at a glance; discovery, genetic basis, recent progress and perspectives.