GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms.
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB Subcellular Location vocabulary mapping.
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:10849009
The PKC targeting protein RACK1 interacts with the Epstein-Barr virus activator protein BZLF1.
PMID:11046044
Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor.
PMID:11278757
The PTPmu protein-tyrosine phosphatase binds and recruits the scaffolding protein RACK1 to cell-cell contacts.
PMID:11279199
The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1.
PMID:11312657
Rack1 binds HIV-1 Nef and can act as a Nef-protein kinase C adaptor.
PMID:12809483
ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways.
PMID:12958311
The scaffolding protein RACK1 interacts with androgen receptor and promotes cross-talk through a protein kinase C signaling pathway.
PMID:14500341
Alternative splicing of the human proto-oncogene c-H-ras renders a new Ras family protein that trafficks to cytoplasm and nucleus.
PMID:15159402
Identification of interaction partners and substrates of the cyclin A1-CDK2 complex.
PMID:15166316
Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms.
PMID:17108144
Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor.
PMID:17956333
Interaction of integrin beta1 with cytokeratin 1 in neuroblastoma NMB7 cells.
PMID:18057008
Cell surface levels of organellar Na+/H+ exchanger isoform 6 are regulated by interaction with RACK1.
PMID:18194455
Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility.
PMID:18420585
RACK1 and CIS mediate the degradation of BimEL in cancer cells.
PMID:18816594
mrtl-A translation/localization regulatory protein encoded within the human c-myc locus and distributed throughout the endoplasmic and nucleoplasmic reticular network.
PMID:18954305
Structural basis and specificity of human otubain 1-mediated deubiquitination.
PMID:19056867
Large-scale proteomics and phosphoproteomics of urinary exosomes.
PMID:19451233
Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation.
PMID:19674157
Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4.
PMID:19767770
A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
PMID:19785988
RACK1 associates with CLEC-2 and promotes its ubiquitin-proteasome degradation.
PMID:20010870
Copine-III interacts with ErbB2 and promotes tumor cell migration.
PMID:20080539
The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase.
PMID:20103773
A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells.
PMID:20499158
RACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathway.
PMID:20541605
RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL.
PMID:20573744
A stimulatory role for the La-related protein 4B in translation.
PMID:20819076
Interaction with receptor for activated C-kinase 1 (RACK1) sensitizes the phosphodiesterase PDE4D5 towards hydrolysis of cAMP and activation by protein kinase C.
PMID:20871634
Regulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasiveness.
PMID:21098120
La-related protein 4 binds poly(A), interacts with the poly(A)-binding protein MLLE domain via a variant PAM2w motif, and can promote mRNA stability.
PMID:21146485
Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40.
PMID:21347310
The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function.
PMID:21525958
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans.
PMID:21750715
The inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effects.
PMID:21988832
Toward an understanding of the protein interaction network of the human liver.
PMID:22013210
The unfolded protein response: integrating stress signals through the stress sensor IRE1α.
PMID:22210188
Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1.
PMID:22658674
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
PMID:22681889
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
PMID:23636399
Structures of the human and Drosophila 80S ribosome.
PMID:23651062
RACK1 (receptor for activated C-kinase 1) interacts with FBW2 (F-box and WD-repeat domain-containing 2) to up-regulate GCM1 (glial cell missing 1) stability and placental cell migration and invasion.
PMID:23866081
Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells.
PMID:24006492
Endosomal acidification by Na+/H+ exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling.
PMID:24947010
DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosis.
PMID:25468996
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
PMID:25901680
Structure of the human 80S ribosome.
PMID:25910212
Widespread macromolecular interaction perturbations in human genetic disorders.
PMID:28132843
ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:29743600
Trafficking, localization and degradation of the Na(+),HCO(3)(-) co-transporter NBCn1 in kidney and breast epithelial cells.
PMID:32296183
A reference map of the human binary protein interactome.
PMID:32467643
Dual functions of Rack1 in regulating Hedgehog pathway.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:37712706
The matrix protein of respiratory syncytial virus suppresses interferon signaling via RACK1 association.
PMID:38190388
A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval invasion through binding to RACK1 and activating MAPK/ERK1/2 pathway.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
PMID:9584165
RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells.
Reactome:R-HSA-5626962
RACK1 localized in cytosol (Reactome).
Reactome:R-HSA-5626981
RACK1 localized in cytosol (Reactome).
Reactome:R-HSA-5626982
RACK1 localized in cytosol (Reactome).