fadA (Aspergillus nidulans) — curation notes

UniProt Q00743 (GPA1_EMENI / FadA). G-alpha subunit; repressive gating tier of the conidiation_regulatory_cascade module.
- Active (GTP-bound) FadA drives proliferation and represses conidiation; antagonized by the RGS protein FlbA. PMID:8895563.
- Core MF GO:0003925 G protein activity; in heterotrimeric G-protein complex (GO:0005834).
- Over-annotations flagged: GO:0045461 ST biosynthetic process, GO:0044550 secondary metabolite biosynthetic process, GO:0042318 penicillin biosynthetic process (FadA is a signaling subunit, not a biosynthetic enzyme → regulation terms).

2026-10-01 re-review (GOA refresh)

• The IEA row GO:0003924 GTPase activity / GO_REF:0000120 (combined automated) is no longer present in the current GOA snapshot; marked retired: true (review kept). Its current replacement is the GO_REF:0000002 InterPro2GO row (IPR001019|IPR002975), reviewed as ACCEPT. Other judgments re-audited; no changes needed.