Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
DROME/CG3515/CG3515-uniprot.txt
Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.
The COMPASS family of H3K4 methylases in Drosophila.
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Fly Set1/COMPASS purified via tagged Wdr82 (CG17293) contains dSet1, dCXXC1, dDpy30, dRbbp5, Ash2 and Wds; CG17293 is very closely related to WDR82. CG3515 is not reported in these S2-cell purifications.
"Sequence searches and alignments of these proteins with human and yeast proteins revealed that CG17293 is very closely related to Wdr82"
The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3.
Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation.
FlyBase gene report for CG3515
CG3515 SWD2-family paralog comparison (re-review)