Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis.
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The PA1054-PA1059 cluster encodes a Na+/H+ antiporter; the abstract reports mutation of PA1054 only.
"We disrupted PA1054 (a shaA homologue gene) and determined its effect on Na+ tolerance during growth, Na+ efflux, and pathogenicity in mice."
Single site mutations in the hetero-oligomeric Mrp antiporter from alkaliphilic Bacillus pseudofirmus OF4 that affect Na+/H+ antiport activity, sodium exclusion, individual Mrp protein levels, or Mrp complex formation.
Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea.
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MrpG-P81A abolishes Na+/H+ antiport but still complements Na+ sensitivity.
"MrpG-P81A in category 7 did not retain Na+/H+ antiport activity, but it was able to complement the sodium sensitivity of the E. coli KNabc."
Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations.
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MrpG is a three-helix membrane subunit of the Mrp complex.
"Each of the small subunits MrpC, MrpF, and MrpG consists of a linear arrangement of three TMH each."
Structure of an Ancient Respiratory System.
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MrpG corresponds to MBH subunit C; MrpG Pro81 is needed for antiport.
"Indeed, MBH subunit C P88 is equivalent to P81 in MrpG and in a previous study it was demonstrated that the H+/Na+ antiporter activity of Mrp was abolished when P81 is substituted by an alanine or a glycine"
UniProt entry Q9I4R5 (Q9I4R5_PSEAE)
Composition of PAINT node PTN002162936 (PTHR34703) and its leaf IBAs