Gene Ontology annotation by the MGI curatorial staff, curated orthology

Requirement for beta-catenin in anterior-posterior axis formation in mice.

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.

Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm.

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor.

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.

A role for Wnt signalling in self-renewal of haematopoietic stem cells.

Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation.

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis.

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.

The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility.

Deletion of beta-catenin impairs T cell development.

Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin.

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon.

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation.

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.

Beta-catenin regulates differentiation of respiratory epithelial cells in vivo.

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.

APC inhibits ERK pathway activation and cellular proliferation induced by RAS.

Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin.

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis.

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development.

Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors.

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling.

An FGF-WNT gene regulatory network controls lung mesenchyme development.

Tissue-specific requirements of beta-catenin in external genitalia development.

Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature.

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney.

Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.

Both the RGS domain and the six C-terminal amino acids of mouse Axin are required for normal embryogenesis.

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction.

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.

A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway.

Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation.

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary.

Expression analysis of an evolutionarily conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon.

ASPM regulates Wnt signaling pathway activity in the developing brain.

Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics.

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.

Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse.

Canonical WNT signaling components in vascular development and barrier formation.

Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.

Lack of beta-catenin affects mouse development at gastrulation.

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation.

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs.

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter.

Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge.

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin.

Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation.

Sequential roles of Hedgehog and Wnt signaling in osteoblast development.

Pax3 functions at a nodal point in melanocyte stem cell differentiation.

Wnt signalling induces maturation of Paneth cells in intestinal crypts.

Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation.

Essential role of beta-catenin in postnatal bone acquisition.

Loss of adenomatous polyposis coli gene function disrupts thymic development.

Beta-catenin is essential for pancreatic acinar but not islet development.

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells.

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis.

The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression.

Wnt-beta-catenin signaling initiates taste papilla development.

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.

Protein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling.

Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis.

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.

Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut.

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.

beta-Catenin promotes respiratory progenitor identity in mouse foregut.

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development.

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.

Biochemical and structural characterization of β-catenin interactions with nonphosphorylated and CK2-phosphorylated Lef-1.

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program.

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.

Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation.

Conditional Knockout of Breast Carcinoma Amplified Sequence 2 (BCAS2) in Mouse Forebrain Causes Dendritic Malformation via β-catenin.

The Shisa3 knockout mouse exhibits normal bone phenotype.

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Functional domains of axin. Importance of the C terminus as an oligomerization domain.

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin.

Identification of a novel beta-catenin-interacting protein.

Structure of the dimerization and beta-catenin-binding region of alpha-catenin.

Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein.

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover.

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development.

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.

alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development.

Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures.

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.

Colorectal cancer in mice genetically deficient in the mucin Muc2.

Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis.

Regulation of Wnt signaling during adipogenesis.

TCL1 participates in early embryonic development and is overexpressed in human seminomas.

Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development.

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.

Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta.

Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability.

Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells.

Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism.

NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.

T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells.

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy.

Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis.

Foxj1 is required for apical localization of ezrin in airway epithelial cells.

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables.

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways.

RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.

alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion.

The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate.

Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.

Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin.

Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin.

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.

Beta-catenin is temporally regulated during normal liver development.

Sox1 acts through multiple independent pathways to promote neurogenesis.

Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact.

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.

Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice.

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice.

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation.

Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast.

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling.

Gene expression profile analysis of mouse colon embryonic development.

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts.

E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.

The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.

Functional interaction between beta-catenin and FOXO in oxidative stress signaling.

MAGI1 recruits Dll1 to cadherin-based adherens junctions and stabilizes it on the cell surface.

Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.

Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis.

Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network.

Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity.

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development.

Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.

Desmocollin 3 is required for pre-implantation development of the mouse embryo.

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production.

The transitional junction: a new functional subcellular domain at the intercalated disc.

Patched1 functions as a gatekeeper by promoting cell cycle progression.

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.

Apc tumor suppressor gene is the "zonation-keeper" of mouse liver.

C3G regulates the size of the cerebral cortex neural precursor population.

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation.

Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT).

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung.

Distinct subdomain organization and molecular composition of a tight junction with adherens junction features.

Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling.

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.

Targeted disruption of the murine large nuclear KIAA1440/Ints1 protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death.

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development.

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88.

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.

Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.

FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen.

SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability.

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.

Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures.

Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype.

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling.

Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction.

Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis.

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway.

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2.

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses.

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification.

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.

A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling.

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure.

The small GTPase Rac1 regulates auditory hair cell morphogenesis.

Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged.

Epicardial-myocardial signaling directing coronary vasculogenesis.

Conductin/axin2 and Wnt signalling regulates centrosome cohesion.

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain.

The apical complex couples cell fate and cell survival to cerebral cortical development.

The TRPV4 channel contributes to intercellular junction formation in keratinocytes.

Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease.

Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter.

Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation.

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.

The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation.

Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development.

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development.

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion.

A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins.

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size.

Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin.

Ezrin-mediated apical integrity is required for intestinal homeostasis.

Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays.

A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection.

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary.

Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia.

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway.

Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes.

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin.

mrhl RNA, a long noncoding RNA, negatively regulates Wnt signaling through its protein partner Ddx5/p68 in mouse spermatogonial cells.

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties.

Physiological role of β-catenin/TCF signaling in neurons of the adult brain.

β-catenin is essential for efficient in vitro premyogenic mesoderm formation but can be partially compensated by retinoic acid signalling.

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.

Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.

Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells.

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.

Flotillin microdomains stabilize cadherins at cell-cell junctions.

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.

POPX2 phosphatase regulates the KIF3 kinesin motor complex.

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation.

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.

Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease.

Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.

TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis.

Resveratrol-Induced Vascular Progenitor Differentiation towards Endothelial Lineage via MiR-21/Akt/β-Catenin Is Protective in Vessel Graft Models.

Transmembrane protein 64 reciprocally regulates osteoblast and adipocyte differentiation by modulating Wnt/β-catenin signaling.

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis.

SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination.

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis.

Plakophilin-1, a Novel Wnt Signaling Regulator, Is Critical for Tooth Development and Ameloblast Differentiation.

Antagonistic Regulation of Intercellular Cohesion by Plakophilins 1 and 3.

A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.

Homeobox protein MSX-1 inhibits expression of bone morphogenetic protein 2, bone morphogenetic protein 4, and lymphoid enhancer-binding factor 1 via Wnt/β-catenin signaling to prevent differentiation of dental mesenchymal cells during the late bell stage.

The mouse Jhy gene regulates ependymal cell differentiation and ciliogenesis.

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.

TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.

Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis.

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.

Immunotoxicologic effects of ethylene dibromide in the mouse and their modulation by the estrous cycle.

Expression of catenins during mouse embryonic development and in adult tissues.

Expression and cell membrane localization of catenins during mouse preimplantation development.

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

A specific domain in alpha-catenin mediates binding to beta-catenin or plakoglobin.

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.

Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice.

Murine Axin1 is dephosphorylated by PP2A leading to reduced binding affinity with beta-catenin

Gata4 and Lef1:Ctnnb1 bind the Isl1 gene

Lef1 or Tcf7 (tcf1) and Ctnnb1 bind the Tbxt (T, Brachyury) gene

Cdh19 associates with catenins

Tbx6 and Lef1:Ctnnb1 bind the Dll1 gene

Tbx6 and Lef1:Ctnnb1 bind the Msgn1 gene

Tcf7l2:Ctnnb1, Foxa2, Mixl1, and Gata4 bind the Sox17 gene

Lef1:Ctnnb1, Nicd (Notch), and Tbx6 bind the Hes7 gene in presomitic mesoderm

Msgn1 and Lef1:Ctnnb1 bind the Dll1 gene in presomitic mesoderm

Hes7 binds the Hes7 gene

Phosphorylation of Kdr and Flt4 in Pecam1:Cdh5:Kdr:Flt4:Ctnnb1 in response to shear stress

Phosphorylation of Pi3k in Pecam1:Cdh5:PiK3ca,b,d:Pik3r2:p-799,Y1052,Y1172-Kdr:p-Y1063,Y1230-Flt4:Ctnnb1

Pik3ca,b,d:Pik3r2 (Pi3k) binds p-Y799,Y1052,Y1172-Kdr in Pecam1:Cdh5:p-Y799,Y1052,Y1172-Kdr:p-Y1063,Y1230-Flt4:Ctnnb1

Phospho-Pi3k in p-Pecam1:Cdh5:Pik3ca,b,d:p-Y458-Pik3r2:p-Y799,Y1052,Y1172-Kdr:p-Y1063,Y1230-Flt4:Ctnnb1 phosphorylates phosphatidylinositol-4,5-bisphosphate to yield phosphatidylinositol-3,4,5-trisphosphate

Ctnna1 binds to CDH11-bound Ctnnb1

Falcon deep research synthesis for mouse Ctnnb1