Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein.

Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Gene Ontology annotation of human sequence-specific DNA binding transcription factors (DbTFs) based on the TFClass database

Combined Automated Annotation using Multiple IEA Methods

Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4.

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.

Functional analyses of three Csx/Nkx-2.5 mutations that cause human congenital heart disease.

Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.

Csx/Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart.

Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome.

A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5.

Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block.

Common arterial trunk associated with a homeodomain mutation of NKX2.6.

CSX/Nkx2.5 modulates differentiation of skeletal myoblasts and promotes differentiation into neuronal cells in vitro.

Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.

The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases.

MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines.

Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier.

NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes.

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity.

Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein.

New mutations in ZFPM2/FOG2 gene in tetralogy of Fallot and double outlet right ventricle.

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.

Crystal structure of the human NKX2.5 homeodomain in complex with DNA target.

Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5.

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block.

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

GATA4 Loss-of-Function Mutation and the Congenitally Bicuspid Aortic Valve.

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.

A reference map of the human binary protein interactome.

Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx.

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors.

Congenital heart disease caused by mutations in the transcription factor NKX2-5.

Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5.

NKX2-5 binds the GATA4 gene

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.

Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system.