Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control?
Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus.
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened.
Sticking together and sorting things out: adhesion as a force in development.
Hedgehog acts as a somatic stem cell factor in the Drosophila ovary.
A positive role for patched-smoothened signaling in promoting cell proliferation during normal head development in Drosophila.
Understanding human cancer using Drosophila: Tid47, a cytosolic product of the DnaJ-like tumor suppressor gene l2Tid, is a novel molecular partner of patched related to skin cancer.
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.
Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction.
Patched regulation of axon guidance is by specifying neural identity in the Drosophila nerve cord.
Allocation and specification of the genital disc precursor cells in Drosophila.
Role of the Drosophila patched gene in positional signalling.
The ihog cell-surface proteins bind Hedgehog and mediate pathway activation.
Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster.
A large complex containing Patched and Smoothened initiates Hedgehog signaling in Drosophila.
Patched, the receptor of Hedgehog, is a lipoprotein receptor.
Genetic and biochemical definition of the Hedgehog receptor.
Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling.
A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway.
Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.
Non-cell autonomous control of apoptosis by ligand-independent Hedgehog signaling in Drosophila.
Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover.
Hedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migration.
Cilia-mediated hedgehog signaling in Drosophila.
Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand.
Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.
PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail.
The Hippo pathway acts downstream of the Hedgehog signaling to regulate follicle stem cell maintenance in the Drosophila ovary.
Cytoneme-mediated cell-cell contacts for Hedgehog reception.
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate.
Protein association changes in the Hedgehog signaling complex mediate differential signaling strength.
Dissection of the microRNA Network Regulating Hedgehog Signaling in Drosophila.
Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in Drosophila wing development.
Dual roles for patched in sequestering and transducing Hedgehog.
The role of segment polarity genes during early oogenesis in Drosophila.
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator.
N-HH binds to PTC receptor complex
FlyBase gene description for ptc (DROME)
UniProt entry P18502 (ptc)