GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:8647286
Cloning of a melatonin-related receptor from human pituitary.
PMID:16778767
The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization.
PMID:19699797
GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth.
PMID:21858214
GPR50 interacts with TIP60 to modulate glucocorticoid receptor signalling.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:28898928
Importance of the second extracellular loop for melatonin MT(1) receptor function and absence of melatonin binding in GPR50.
PMID:31900622
GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors.
PMID:32405532
GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17.
PMID:40091563
Orphan GPR50 Restrains Neurite Outgrowth and Cell Migration by Activating the G(12/13) Protein-RhoA Pathway in Neural Progenitor Cells and Tanycytes.
PMID:41495223
Photo-cross-linking-assisted deorphanization deciphers GPR50-L-LEN pairing in metabolism.
PMID:41666959
Structure of the melatonin-related orphan receptor, GPR50.