Gene Ontology annotation through association of InterPro records with GO terms.
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.
Gene Ontology annotation based on curation of immunofluorescence data
Automatic Gene Ontology annotation based on Rhea mapping.
Combined Automated Annotation using Multiple IEA Methods.
Intestinal epithelial cells secrete exosome-like vesicles.
Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway.
HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors.
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.
Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7.
Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation.
Oxidative stress-responsive intracellular regulation specific for the angiostatic form of human tryptophanyl-tRNA synthetase.
A human protein-protein interaction network: a resource for annotating the proteome.
Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA).
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
A mutation in human VAP-B--MSP domain, present in ALS patients, affects the interaction with other cellular proteins.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Defining the membrane proteome of NK cells.
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.
Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer-fluorescence lifetime imaging microscopy in living cells.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Proliferating cell nuclear antigen in the cytoplasm interacts with components of glycolysis and cancer.
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Protein profile of exosomes from trabecular meshwork cells.
Proteomic characterization of the human sperm nucleus.
Toward an understanding of the protein interaction network of the human liver.
A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation.
Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages.
NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-κB activation.
Prolyl oligopeptidase is a glyceraldehyde-3-phosphate dehydrogenase-binding protein that regulates genotoxic stress-induced cell death.
Identification of sperm head proteins involved in zona pellucida binding.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity.
ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function.
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.
Target-selective protein S-nitrosylation by sequence motif recognition.
AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation.
Citrobacter rodentium NleB Protein Inhibits Tumor Necrosis Factor (TNF) Receptor-associated Factor 3 (TRAF3) Ubiquitination to Reduce Host Type I Interferon Production.
Nuclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I protect smooth muscle cells against oxidant-induced cell death.
Architecture of the human interactome defines protein communities and disease networks.
Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells.
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Isolation and complete sequence of a functional human glyceraldehyde-3-phosphate dehydrogenase gene.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
The complete amino acid sequence of human muscle glyceraldehyde 3-phosphate dehydrogenase.
GADPH tetramer dehydrogenates GA3P
GAPDH tetramers reduce 1,3BPG to GA3P
Deep research on GAPDH function
Falcon deep research on GAPDH function (Edison Scientific Literature, 2026-05-29): canonical glycolytic activity, N-GAPDH cascade (Cys-150/Lys-225/Siah1), DNA-repair interaction with Pol β, and PTM-driven regulation (crotonylation K194/K219, HDAC9-deacetylation K219).
Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch.
Targeting Moonlighting Enzymes in Cancer.
Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility.
Housekeeping protein-coding genes interrogated with tissue and individual variations.
Effect of HDAC9-induced deacetylation of glycolysis-related GAPDH lysine 219 on rotavirus replication in rotavirus-infected Caco-2 cells.