Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
Gene Ontology annotation based on curation of immunofluorescence data
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation.
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Trx translocates to nucleus after IR exposure
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Trx-Ref-1 interaction enhanced after radiation
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Trx activates AP-1 DNA binding activity
Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway
S-nitrosation of thioredoxin in the nitrogen monoxide/superoxide system activates apoptosis signal-regulating kinase 1.
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1.
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine
Cross-reactivity and 1.4-A crystal structure of Malassezia sympodialis thioredoxin (Mala s 13), a member of a new pan-allergen family.
Buried S-nitrosocysteine revealed in crystal structures of human thioredoxin
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Crystal structure of S-nitrosylated Trx1
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S-nitrosylation at Cys62 and Cys69
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Homodimer formation through Cys73
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.
Auto- and cross-reactivity to thioredoxin allergens in allergic bronchopulmonary aspergillosis
Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin
Human thioredoxin reactivity-structure/function relationship
Positive regulation of apoptosis signal-regulating kinase 1 signaling by ZPR9 protein, a zinc finger protein.
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway
Reactivation of oxidized PTP1B and PTEN by thioredoxin 1
Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1.
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Trx directly associates with Ref-1/APE1
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Requires Trx catalytic cysteines
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Nuclear translocation upon PMA treatment
Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
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Trx forms homodimers through Cys73
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pH-dependent dimerization
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Asp60 regulates dimerization
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.
Large-scale mapping of human protein-protein interactions by mass spectrometry.
CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1.
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics.
Toward an understanding of the protein interaction network of the human liver.
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.
Architecture of the human interactome defines protein communities and disease networks.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS(G13D).
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Reactome pathway annotation
Reactome pathway - Ribonucleotide reductase reaction
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway annotation
Reactome pathway - TXNIP binding to reduced thioredoxin
Reactome pathway annotation
Deep research on TXN function
Cyberian deep research on TXN function