GID1B (At3g63010, UniProt Q9LYC1) curation notes
Identity
- UniProt Q9LYC1 GID1B_ARATH, "Gibberellin receptor GID1B"; synonyms CXE14, GID1L2; locus At3g63010. Verified in GID1B-uniprot.txt.
- PANTHER PTHR23024:SF98 (GIBBERELLIN RECEPTOR GID1B) within PTHR23024 (ARYLACETAMIDE DEACETYLASE).
Key findings (with provenance)
- All three AtGID1s bind GA, highest affinity for GA4; GID1B is ~10-fold higher affinity with narrow pH range PMID:16709201.
- GA-dependent DELLA interaction in yeast PMID:16709201.
- Receptor function: each AtGID1 rescues rice gid1-1 PMID:16709201.
- Triple mutant is GA-insensitive PMID:17521411; gid1a gid1b has short stamens and low fertility PMID:17521411.
- Positive regulators of GA signaling PMID:17194763.
- No hydrolase activity in GID1 receptors PMID:24961590.
- Fruit/ovule: GID1B mainly in ovules/funiculi; gid1a gid1b reduced seed-set with WT pollen PMID:24961590.
- GID1B overexpression relieves sly1-2 seed dormancy without DELLA proteolysis PMID:23818171.
- GID1b transcript rises with after-ripening PMID:26136598.
- Separate eudicot GID1b clade; GID1b cannot replace GID1ac in germination PMID:21778177.
- Falcon deep research (GID1B-deep-research-falcon.md) adds: Yamamoto et al. 2010 Plant Cell (GA-independent GID1B-GAI binding in yeast, loop swap) and root-biased function; not cached as PMIDs here.
Curation decisions
- Hydrolase activity (IEA InterPro, IBA PTN009058710): REMOVE, pseudoenzyme over-propagation.
- NOT response to gibberellin (CAFA IMP/IGI, PMID:24961590): REMOVE; negation based on absence of phenotype in mutants retaining redundant paralogs, contradicted by receptor biochemistry.
- Negative regulation of gene expression (IGI): over-annotation (feedback up-regulation of GID1A in gid1b gid1c).
- Protein binding rows: REMOVE per protein-binding policy; the PMID:19429606 (FRIGIDA) row is also REMOVE (2026-10-06), with a note that the cached text never mentions GID1/DELLA (probable IntAct reference mismatch).
- Core: GO:0010331 gibberellin binding; GO:0010476; nucleus. Proposed NTR "gibberellin receptor activity" (as in GID1A).