Manual transfer of experimentally-verified manual GO annotation data to orthologs using Ensembl Compara
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier.
Network organization of the human autophagy system.
The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.
Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
UBA5 mutations cause a new form of autosomal recessive cerebellar ataxia.
Trans-binding mechanism of ubiquitin-like protein activation revealed by a UBA5-UFM1 Complex.
Ufm1 inhibits LPS-induced endothelial cell inflammatory responses through the NF-κB signaling pathway.
Architecture of the human interactome defines protein communities and disease networks.
Trans-binding of UFM1 to UBA5 stimulates UBA5 homodimerization and ATP binding.
Biallelic UFM1 and UFC1 mutations expand the essential role of ufmylation in brain development.
An N-terminal extension to UBA5 adenylation domain boosts UFM1 activation: isoform-specific differences in ubiquitin-like protein activation.
Ribosomal protein RPL26 is the principal target of UFMylation.
A genome-wide ER-phagy screen highlights key roles of mitochondrial metabolism and ER-Resident UFMylation.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.