Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Release Of ADP From Myosin
DGC complex binds laminins
Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC
DGC complex binds AGRN and HSPG2
Detection of dystrophin in the postsynaptic density of rat brain and deficiency in a mouse model of Duchenne muscular dystrophy.
Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.
Expression of recombinant dystrophin and its localization to the cell membrane.
The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein.
The Duchenne muscular dystrophy gene product is localized in sarcolemma of human skeletal muscle.
X chromosome-linked muscular dystrophy (mdx) in the mouse.
Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy.
Identification and characterization of the dystrophin anchoring site on beta-dystroglycan.
Syntrophin binds to an alternatively spliced exon of dystrophin.
Association of aciculin with dystrophin and utrophin.
Breeding of the gad-mdx mouse: influence of genetically induced denervation on dystrophic muscle fibers.
Dystrophin: the long and short of it.
The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives.
Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins.
Expression of dystrophin Dp71 during PC12 cell differentiation.
Increased expression of dystrophin, beta-dystroglycan and adhalin in denervated rat muscles.
Differential association of syntrophin pairs with the dystrophin complex.
Dystrophin and its isoforms in a sympathetic ganglion of normal and dystrophic mdx mice: immunolocalization by electron microscopy and biochemical characterization.
Dystrobrevin and dystrophin: an interaction through coiled-coil motifs.
Dystrophins in neurohypophysial lobe of normal and dehydrated rats: immunolocalization and biochemical characterization.
Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission.
Differential distribution of dystrophins in rat retina.
The demonstration of immunoreactive dystrophin and its developmental expression in perivascular astrocytes.
Different dystrophin-like complexes are expressed in neurons and glia.
In vitro interactions of Caenorhabditis elegans dystrophin with dystrobrevin and syntrophin.
Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.
Contribution of the different modules in the utrophin carboxy-terminal region to the formation and regulation of the DAP complex.
The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy.
Aciculin and its relation to dystrophin: immunocytochemical studies in human normal and Duchenne dystrophy quadriceps muscles.
Assembly of multiple dystrobrevin-containing complexes in the kidney.
Mitochondrial expression of a short dystrophin-like product with molecular weight of 71 kDa.
Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.
Characterization of the intermolecular associations of the dystrophin-associated glycoprotein complex in retinal Müller glial cells.
Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.
Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans.
Caveolin-3 deficiency causes muscle degeneration in mice.
Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities.
Subcellular localization of Dp71 dystrophin isoforms in cultured hippocampal neurons and forebrain astrocytes.
Biochemical and histochemical analysis of 71 kDa dystrophin isoform (Dp71f) in rat brain.
The interaction of dystrophin with beta-dystroglycan is regulated by tyrosine phosphorylation.
Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse.
Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans.
Localization of alpha 7 integrins and dystrophin suggests potential for both lateral and longitudinal transmission of tension in large mammalian muscles.
The expression of dystrophin, alpha-sarcoglycan, and beta-dystroglycan during skeletal muscle regeneration: immunohistochemical and western blot studies.
Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.
Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.
The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families.
Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family.
Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.
Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling.
Loss of intracellular dystrophin: a potential mechanism for myocardial reperfusion injury.
Abnormal development of the diaphragm in mdx:MyoD-/-(9th) embryos leads to pulmonary hypoplasia.
Beta-dystrobrevin interacts directly with kinesin heavy chain in brain.
Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions.
Characterization of ARC, apoptosis repressor interacting with CARD, in normal and dystrophin-deficient skeletal muscle.
Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers.
Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.
Dystrophin Dp71 is required for neurite outgrowth in PC12 cells.
Cloning and characterization of cytokeratins 8 and 19 in adult rat striated muscle. Interaction with the dystrophin glycoprotein complex.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Dystrophin Dp71 in PC12 cell adhesion.
The DNA sequence of the human X chromosome.
Specific interaction of the actin-binding domain of dystrophin with intermediate filaments containing keratin 19.
A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis.
Identification of functional domains in sarcoglycans essential for their interaction and plasma membrane targeting.
Interactions of intermediate filament protein synemin with dystrophin and utrophin.
Role of dystrophins and utrophins in platelet adhesion process.
Developmental regulation of biglycan expression in muscle and tendon.
Nuclear sequestration of delta-sarcoglycan disrupts the nuclear localization of lamin A/C and emerin in cardiomyocytes.
beta-dystrobrevin, a kinesin-binding receptor, interacts with the extracellular matrix components pancortins.
Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.
Association of dystrobrevin and regulatory subunit of protein kinase A: a new role for dystrobrevin as a scaffold for signaling proteins.
Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation.
Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy.
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.
Proteins interacting with Caenorhabditis elegans Galpha subunits.
A quantitative atlas of mitotic phosphorylation.
Dp71f modulates GSK3-beta recruitment to the beta1-integrin adhesion complex.
High incidence of electrocardiogram abnormalities in young patients with duchenne muscular dystrophy.
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle.
Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.
Inhibition of myostatin promotes myogenic differentiation of rat bone marrow-derived mesenchymal stromal cells.
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy.
Oxidative stress by monoamine oxidases is causally involved in myofiber damage in muscular dystrophy.
Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.
SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes.
Initial characterization of the human central proteome.
Characterization of Dp71Δ(78-79), a novel dystrophin mutant that stimulates PC12 cell differentiation.
Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.
Knockdown of dystrophin Dp71 impairs PC12 cells cycle: localization in the spindle and cytokinesis structures implies a role for Dp71 in cell division.
Identification of Dp71e, a new dystrophin with a novel carboxy-terminal end.
Three-dimensional regulation of radial glial functions by Lis1-Nde1 and dystrophin glycoprotein complexes.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics.
Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.
A proteome-scale map of the human interactome network.
Widespread macromolecular interaction perturbations in human genetic disorders.
Structural Basis of Neuronal Nitric-oxide Synthase Interaction with Dystrophin Repeats 16 and 17.
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase.
Architecture of the human interactome defines protein communities and disease networks.
The extracellular matrix protein agrin promotes heart regeneration in mice.
Syntrophin binds directly to multiple spectrin-like repeats in dystrophin and mediates binding of nNOS to repeats 16-17.
Blood-Brain Barrier: From Physiology to Disease and Back.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Dystrophin Dp71 Subisoforms Localize to the Mitochondria of Human Cells.
Generation of dystrophin short product-specific tag-insertion mouse: distinct Dp71 glycoprotein complexes at inhibitory postsynapse and glia limitans.
Structure and assembly of the dystrophin glycoprotein complex.
Native DGC structure rationalizes muscular dystrophy-causing mutations.
Multimodal cell maps as a foundation for structural and functional genomics.
Dystrophin (DMD), Homo sapiens