Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Combined Automated Annotation using Multiple IEA Methods
Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.
The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.
SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.
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The abstract identifies p250R as a large subunit of human SWI/SNF; SSX1 histone binding is a separate result.
"The SYT protein has a unique QPGY domain, which is also
present in the largest subunits, p250 and the newly identified homolog p250R, of
the corresponding SNF/SWI complexes."
SWI/SNF chromatin remodeling and cancer.
Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.
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The study cloned a human hELD/OSA1 sequence; modern ARID1B identity is independently mapped in the notes.
"Here we describe the cloning of
hELD/OSA1, a 189 KDa human homologue of Drosophila Eld/Osa protein, a
constituent of Drosophila SWI/SNF."
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.
REST repression of neuronal genes requires components of the hSWI.SNF complex.
Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.
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Human hOsa2 associates with the ATPases through its C-terminal region.
"Co-precipitation studies indicate that hOsa1 and hOsa2 associate with BRG1 and
hBRM through the C-terminal domain of hOsa."
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Human hOsa2 supports steroid-receptor transcriptional coactivation in the tested cellular contexts.
"In cultured mammalian
cells, hOsa1 and hOsa2 stimulate transcription by the glucocorticoid, estrogen,
and androgen receptors."
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The tested GR reporter effect requires more than the isolated C terminus and is lost with the ARID deletion.
"The glucocorticoid receptor-mediated activation is not
observed with the C-terminal domain or with the hOsa2 polypeptide lacking the
ARID DNA binding domain."
The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.
Identification of a polymorphic, neuron-specific chromatin remodeling complex.
Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.
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Human ARID1B binds DNA without apparent sequence preference.
"Analysis of DNA-binding behaviour indicates that ARID1B
binds DNA in a non-sequence-specific manner similar to p270."
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Native human complexes contain alternative ARID1A or ARID1B subunits.
"Immunocomplex analysis provides direct evidence that
endogenous ARID1B is associated with SWI/SNF-related complexes and indicates
that p270 and ARID1B, similar to the ATPase subunits BRG1 and hBRM, are
alternative, mutually exclusive subunits of the complexes."
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ARID1B associates with both BRG1 and BRM-containing assemblies.
"The ARID-containing
subunits are not specific to the ATPases. Each associates with both BRG1 and
hBRM, thus increasing the number of distinct subunit combinations known to be
present in cells."
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.
Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.
Regulation of dendritic development by neuron-specific chromatin remodeling complexes.
BAF complexes facilitate decatenation of DNA by topoisomerase IIα.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.
Multimodal cell maps as a foundation for structural and functional genomics.
Diversity and specialization of mammalian SWI/SNF complexes.
MITF-M dimer and the SWI/SNF complex bind the TYRP1 promoter
ARID1 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1
DPF1,2,3 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1
SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3
Formation of neuronal progenitor BAF (npBAF)
ARID1B manual source and assay-scope notes
UniProtKB Q8NFD5: ARID1B preserved normal record