Gene Ontology annotation based on Enzyme Commission mapping

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniPathway vocabulary mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by ARBA machine learning models

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation.

UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI.

FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL.

Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection.

Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.

FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex

Monoubiquitination of FANCD2:FANCI

The complex of ATR and ATRIP is recruited to ICL-DNA

ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA

UBA1 conjugates ubiquitin to nuclear E2 enzymes