GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000024
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000108
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000121
RGD ISO annotations to rat from other mammalian species
PMID:10725339
beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2.
PMID:11742073
beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins.
PMID:12167719
Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1.
PMID:12399592
Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins.
PMID:12519791
Role of G protein-coupled receptor kinase 4 and beta-arrestin 1 in agonist-stimulated metabotropic glutamate receptor 1 internalization and activation of mitogen-activated protein kinases.
PMID:12614678
Differential regulation of beta-arrestin 1 and beta-arrestin 2 gene expression in rat brain by morphine.
PMID:14519533
Presence of beta-arrestin-1 immunoreactivity in the cutaneous nerve fibers of rat glabrous skin.
PMID:1517224
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.
PMID:15728179
Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein.
PMID:16325578
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription.
PMID:16899567
G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells.
PMID:17500066
Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2.
PMID:17513300
The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2.
PMID:18523139
Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: the potential role of receptor interaction with beta-arrestins and AP50.
PMID:19254952
Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor.
PMID:19289825
An adrenal beta-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo.
PMID:19339617
17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1.
PMID:20650893
Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.
PMID:20705669
G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling.
PMID:21223624
Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway.
PMID:21857681
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.
PMID:23604254
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
PMID:23886940
Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.
PMID:24378649
PAR-1 activation rescues astrocytes through the PI3K/Akt signaling pathway from chemically induced apoptosis that is exacerbated by gene silencing of β-arrestin 1.
PMID:25016018
Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK.
PMID:25486571
The induction of thioredoxin-1 by epinephrine withdraws stress via interaction with β-arrestin-1.
PMID:26621121
Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis.
PMID:37209686
Structural snapshots uncover a key phosphorylation motif in GPCRs driving β-arrestin activation.
PMID:38175886
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors.
PMID:19171933
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation.
PMID:19915011
GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells.
PMID:11853756
Functionally rodless mice: transgenic models for the investigation of cone function in retinal disease and therapy.
file:rat/Arrb1/Arrb1-uniprot.txt
UniProt P29066 ARRB1_RAT record
file:rat/Arrb1/Arrb1-deep-research-manual.md
Manual literature synthesis for rat Arrb1