Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.
Gene Ontology annotation based on curation of immunofluorescence data
The alpha and beta subunit of the nascent polypeptide-associated complex have distinct functions.
Identification of a novel transcriptional repressor (HEPIS) that interacts with nsp-10 of SARS coronavirus.
Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
A proteome-scale map of the human interactome network.
Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Curator notes on human BTF3 review
UniProt entry for human BTF3 (P20290)
Falcon deep research report for BTF3
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Falcon research supports BTF3 as the NAC-beta subunit, a ribosome-associated nascent-chain triage factor that prevents inappropriate ER targeting of non-secretory nascent proteins.
"BTF3 is mechanistically anchored in ribosome biology through its identity as NAC-beta"