Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Annotation inferences using phylogenetic trees

human/AFAP1L2/AFAP1L2-uniprot.txt

HORSE/AFAP1L2/AFAP1L2-uniprot.txt

HORSE/AFAP1L2/AFAP1L2-bioinformatics/RESULTS.md

HORSE/AFAP1L2/AFAP1L2-bioinformatics/RESULTS-rereview.md

interpro/panther/PTHR14338/PTHR14338-paint.tsv

XB130, a novel adaptor protein for signal transduction.

XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.

Phosphatidylinositol 3-kinase-binding protein, PI3KAP/XB130, is required for cAMP-induced amplification of IGF mitogenic activity in FRTL-5 thyroid cells.

Adaptor protein XB130 is a Rac-controlled component of lamellipodia that regulates cell motility and invasion.

Phosphatidylinositol 3-Kinase-Associated Protein (PI3KAP)/XB130 Crosslinks Actin Filaments through Its Actin Binding and Multimerization Properties In Vitro and Enhances Endocytosis in HEK293 Cells.

XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes.

XB130/Tks5 scaffold protein interaction regulates Src-mediated cell proliferation and survival.