Annotation inferences using phylogenetic trees

IBA annotations for A0A3B6RKV1 come from PAINT node PANTHER:PTN001753861 (PTHR12480). Nucleus is seeded by AT5G06550 (JMJ22), Q386V9 and Q96S16 (JMJD8); cis-regulatory region sequence-specific DNA binding is seeded by AT5G06550 alone. JMJ22's histone demethylase activity (IGI) and its process annotations were not propagated.

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

GO_REF:0000104

Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features

PMID:22483719

Control of seed germination by light-induced histone arginine demethylation activity.

JMJ20 and JMJ22 act redundantly as positive regulators of seed germination. Upon PHYB activation, JMJ20/JMJ22 are derepressed, resulting in increased gibberellic acid levels through the removal of repressive histone arginine methylations (H4R3me2) at GA3ox1/GA3ox2, which in turn promotes seed germination.

"the histone arginine demethylases, JMJ20 and JMJ22, act redundantly as positive regulators of seed germination"

PMID:25533953

An Arabidopsis gene regulatory network for secondary cell wall synthesis.

file:WHEAT/A0A3B6RKV1/A0A3B6RKV1-deep-research-falcon.md

Deep research report for A0A3B6RKV1 (LOC123148885) in Triticum aestivum

The falcon report places LOC123148885 in the KDM5/JARID1 (H3K4 demethylase) subfamily. This is contradicted by PANTHER (PTHR12480:SF21), InterPro IPR050910 and the F-box/JmjC domain architecture, which lacks JmjN, ARID, PHD and FYR domains.

"The primary function of LOC123148885 can be inferred from its membership in the KDM5/JARID1 subfamily of JmjC domain-containing histone demethylases."

file:WHEAT/A0A3B6RKV1/A0A3B6RKV1-hypotheses/core-function-1-go-0032452/openscientist.md

OpenScientist deep research report on core function hypothesis for A0A3B6RKV1 histone demethylase activity

Corrected the KDM5/JARID1 call to a JMJ22-like assignment based on PANTHER, InterPro and domain architecture.

file:WHEAT/A0A3B6RKV1/A0A3B6RKV1-uniprot.txt

UniProtKB A0A3B6RKV1 record

file:WHEAT/A0A3B6RKV1/A0A3B6RKV1-bioinformatics/RESULTS-rereview.md

A0A3B6RKV1 vs Arabidopsis JMJ22 and human JMJD8 alignment and residue mapping

Wheat, JMJ22 and JMJD8 share PANTHER SF21; JMJ20 is in SF6. Wheat vs JMJ22 global identity is 62.6% (JmjC 77%), with conserved F-box and conserved Fe(II) ligands H330/D332/H413.

"AtJMJ22 JmjC 279-439 maps to wheat 285-445 (77.0% identity)."

file:WHEAT/A0A3B6RKV1/A0A3B6RKV1-bioinformatics/Q67XX3-JMJ22-uniprot.txt

UniProtKB Q67XX3 (Arabidopsis JMJ22) record, fetched 2026-10-20

file:WHEAT/A0A3B6RKV1/A0A3B6RKV1-bioinformatics/Q96S16-JMJD8-uniprot.txt

UniProtKB Q96S16 (human JMJD8) record, fetched 2026-10-20