Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling.
Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3.
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OSM-3 is autoinhibited in compact conformation with low ATPase activity
"displays low microtubule-stimulated adenosine triphosphatase (ATPase) activity"
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OSM-3 is a plus-end directed processive motor when activated
"As expected, OSM-3 was an active plus end-directed motor in a microtubule gliding assay"
Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors.
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OSM-3 and kinesin-II cooperate for IFT in middle segment
"heterotrimeric kinesin-II and homodimeric OSM-3-kinesin, which cooperate to move the same intraflagellar transport (IFT) particles along microtubule (MT) doublets"
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OSM-3 forms homodimeric kinesin complexes
"heterotrimeric kinesin-II and homodimeric OSM-3-kinesin"
Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans.
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osm-3 mutations cause structurally defective chemosensory cilia
"Dauer-defective mutations in nine genes cause structurally defective chemosensory cilia, thereby blocking chemosensation"
Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans.
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OSM-3 functions with kinesin-II in middle segment IFT
"anterograde intraflagellar transport (IFT) is mediated by two kinesin-2 complexes, kinesin II and OSM-3 kinesin"
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OSM-3 alone mediates distal segment IFT
"OSM-3 alone mediates transport in the distal segments"
Endocytosis genes facilitate protein and membrane transport in C. elegans sensory cilia.
The BBSome controls IFT assembly and turnaround in cilia.
A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4.
A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis.
Multiple chemosensory defects in daf-11 and daf-21 mutants of Caenorhabditis elegans.
Two heteromeric kinesin complexes in chemosensory neurons and sensory cilia of Caenorhabditis elegans.
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OSM-3 forms homodimeric kinesin complexes (CeOsm-3)
"heterotrimeric CeKinesin-II and dimeric CeOsm-3"
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OSM-3 localizes to amphid, inner labial, and phasmid neurons
"both CeKinesin-II and CeOsm-3 are expressed in amphid, inner labial, and phasmid chemosensory neurons"
Deep research report on osm-3