Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Combined Automated Annotation using Multiple IEA Methods
Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF.
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A recG::Gm mutant is hypersensitive to UV; recG in trans partially restores tolerance.
"The recG ::Gm mutant was hypersensitive to UV and was killed by more than 5 log units within 20 s of irradiation."
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The recG mutant is less resistant to H2O2 and cumene hydroperoxide.
"Still, recG appeared to be essential for optimal resistance to H 2 O 2 and CHP, and the recG mutant could be complemented by the recG gene in trans ."
Involvement of DNA helicases in chromate resistance by Pseudomonas aeruginosa PAO1.
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recG (PA5345) transposon mutant is chromate-hypersensitive and complemented by recG.
"The chromate resistance phenotype in mutants GGP-64 and AJ-22 was restored by cosmids bearing wild type ruvB or recG genes, respectively."
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The mutants are also sensitive to tellurite, selenite and mitomycin C.
"both mutant strains showed an increased susceptibility to the toxic oxyanions tellurite and selenite as well as to mitomycin C, but not to arsenite, paraquat and hydrogen peroxide."
ATP-dependent RecG helicase is required for the transcriptional regulator OxyR function in Pseudomonas species.
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Purified RecG binds palindromic promoters and, with ATP, generates linear DNA that OxyR binds.
"The OxyR tetramer preferentially binds to promoters after RecG has generated linear DNA in the presence of ATP"
recG (PA5345) review notes