Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
RGD ISO annotations to rat from other mammalian species
Rat testicular Src: normal distribution and involvement in ethylene glycol monomethyl ether-induced apoptosis.
Nonreceptor tyrosine protein kinase pp60c-src in spatial learning: synapse-specific changes in its gene expression, tyrosine phosphorylation, and protein-protein interactions.
pp60(c-src) modulates microvascular endothelial phenotype and in vitro angiogenesis.
NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A(NR2A) and interaction of Pyk2 and Src with NR2A after transient cerebral ischemia and reperfusion.
Regulation of an ERG K+ current by Src tyrosine kinase.
Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria.
Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domains.
Role of c-SRC and ERK in acid-induced activation of NHE3.
Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src.
pp60c-Src Kinase mediates growth effects of the full-length precursor progastrin1-80 peptide on rat intestinal epithelial cells, in vitro.
Interaction between chicken protein tyrosine phosphatase 1 (CPTP1)-like rat protein phosphatase 1 (PTP1) and p60(v-src) in v-src-transformed Rat-1 fibroblasts.
Tyrosine kinase and tyrosine phosphatase participate in regulation of interactions of NMDA receptor subunit 2A with Src and Fyn mediated by PSD-95 after transient brain ischemia.
Active Src expression is induced after rat peripheral nerve injury.
Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study.
Interactions between Src family protein tyrosine kinases and PSD-95.
Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation.
Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver.
Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells.
Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2.
Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase.
Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin.
Src tyrosine kinase regulates insulin-induced activation of protein kinase C (PKC) delta in skeletal muscle.
Protein kinases and adherens junction dynamics in the seminiferous epithelium of the rat testis.
PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells.
Regulation of ectoplasmic specialization dynamics in the seminiferous epithelium by focal adhesion-associated proteins in testosterone-suppressed rat testes.
Caveolin-1 facilitates mechanosensitive protein kinase B (Akt) signaling in vitro and in vivo.
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.
Suppression of Pyk2 attenuated the increased tyrosine phosphorylation of NMDA receptor subunit 2A after brain ischemia in rat hippocampus.
Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes.
c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats.
Evidence for multiple Src binding sites on the alpha1c L-type Ca2+ channel and their roles in activity regulation.
c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells.
Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels.
[Proto-oncogene c-src regulates the viability of rat spermatogonial stem cells in vitro through phosphorylated signal transducer and activator of transcription-3].
Localization of PTP-1B, SHP-2, and Src exclusively in rat brain mitochondria and functional consequences.
Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.
FGF-1-induced reactions for biogenesis of apoE-HDL are mediated by src in rat astrocytes.
Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration.
Lipoteichoic acid induces matrix metalloproteinase-9 expression via transactivation of PDGF receptors and NF-kappaB activation in rat brain astrocytes.
Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src.
The regulatory domain of protein kinase C delta positively regulates insulin receptor signaling.
Butyrate reduced lipopolysaccharide-mediated macrophage migration by suppression of Src enhancement and focal adhesion kinase activity.
Regulation of coronary arterial BK channels by caveolae-mediated angiotensin II signaling in diabetes mellitus.
Transduced PDZ1 domain of PSD-95 decreases Src phosphorylation and increases nNOS (Ser847) phosphorylation contributing to neuroprotection after cerebral ischemia.
EV71 induces COX-2 expression via c-Src/PDGFR/PI3K/Akt/p42/p44 MAPK/AP-1 and NF-kappaB in rat brain astrocytes.
Learning induces neurotrophin signaling at hippocampal synapses.
Decrease in dietary K intake stimulates the generation of superoxide anions in the kidney and inhibits K secretory channels in the CCD.
Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury.
Periodic mechanical stress enhances rat chondrocyte area expansion and migration through Src-PLCgamma1-ERK1/2 signaling.
Functional impact of PTP1B-mediated Src regulation on oxidative phosphorylation in rat brain mitochondria.
Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration.
Differential expression of protooncogenes related to transformation and cancer progression in rat myoblasts.
Proto-oncogene expression in proliferating and differentiating cardiac and skeletal muscle.
Localization of pp60c-src in growth cone of PC12 cell.
The N2-Src neuronal splice variant of C-Src has altered SH3 domain ligand specificity and a higher constitutive activity than N1-Src.
Inhibition of N1-Src kinase by a specific SH3 peptide ligand reveals a role for N1-Src in neurite elongation by L1-CAM.
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration.
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.
Donepezil promotes neurogenesis via Src signaling pathway in a rat model of chronic cerebral hypoperfusion.
pp60c-src expression in rat spermatogenesis.
Angiotensin II activates pp60c-src in vascular smooth muscle cells.
Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.
Prolactin receptor is associated with c-src kinase in rat liver.
Angiotensin II controls p21ras activity via pp60c-src.
Oxidative stress induces tyrosine phosphorylation of PDGF alpha-and beta-receptors and pp60c-src in mesangial cells.
A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation.
NMDA channel regulation by channel-associated protein tyrosine kinase Src.
G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60c-src and p21ras.
Phosphorylation of ITIM in SIRP alpha
Src,Yes1 phosphorylate Yap1
Src phosphorylates GluN2 (Grin2) subunits of NMDARs
UniProt entry for rat Src (Proto-oncogene tyrosine-protein kinase Src)
Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation.
Manual literature synthesis for rat Src